Prayer camps are booming with the advent of HIV/AIDS, with Africa becoming the epicentre since its discovery in 1981 in the United States. The inaccessibility of ARVs due to impoverishment, accentuated by conflicts of all kinds, has paved the way for a new type of therapy that is less expensive and very accessible: miraculous healings in the Name of Jesus. This therapy, which defies science, led us to ask the following question: do the knowledge and practices of prayer camp staff contribute to the fight against HIV/AIDS?We set out to conduct a descriptive cross-sectional study, the general aim of which was to investigate the knowledge, attitudes and practices of prayer camp staff in the Aboisso Department in relation to HIV/AIDS. The study was based on a random selection of 10 prayer camps out of a total of 15 identified. The DE LAROCHE sampling method was used and the sample consisted of 100 staff members.