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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Korsakoff''s syndrome (Korsakoff''s psychosis, amnesic-confabulatory syndrome; also spelled "Korsakov''s Syndrome"), is a brain disorder caused by the lack of thiamine (vitamin B1) in the brain. The syndrome is named after Sergei Korsakoff, the neuropsychiatrist who popularized the theory. There are six major symptoms of Korsakoff''s syndrome:1. anterograde amnesia and 2. retrograde amnesia, severe memory loss 3. confabulation, that is, invented memories which are then taken as true due to gaps in memory sometimes associated with blackouts. 4. meager content in conversation. 5. lack of insight. 6. apathy - the patients lose interest in things quickly and generally appear indifferent to change.