Landmark Papers in Pain
Seminal Papers in Pain with Expert Commentaries
Herausgeber: Farquhar-Smith, Paul; Jaggar, Siân; Beaulieu, Pierre
Landmark Papers in Pain
Seminal Papers in Pain with Expert Commentaries
Herausgeber: Farquhar-Smith, Paul; Jaggar, Siân; Beaulieu, Pierre
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Landmark Papers in Pain discusses 83 core examples of novel research and seminal papers that revolutionised Pain Medicine. Leading specialists give detailed commentaries on the significance of literature which stimulated a paradigm shift in therapeutic strategy or acted as a catalyst for improved clinical methods in the field.
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Landmark Papers in Pain discusses 83 core examples of novel research and seminal papers that revolutionised Pain Medicine. Leading specialists give detailed commentaries on the significance of literature which stimulated a paradigm shift in therapeutic strategy or acted as a catalyst for improved clinical methods in the field.
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Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Produktdetails
- Produktdetails
- Landmark Papers In
- Verlag: Oxford University Press
- Seitenzahl: 334
- Erscheinungstermin: 26. September 2018
- Englisch
- Abmessung: 244mm x 170mm x 20mm
- Gewicht: 594g
- ISBN-13: 9780198834359
- ISBN-10: 0198834357
- Artikelnr.: 53446546
- Landmark Papers In
- Verlag: Oxford University Press
- Seitenzahl: 334
- Erscheinungstermin: 26. September 2018
- Englisch
- Abmessung: 244mm x 170mm x 20mm
- Gewicht: 594g
- ISBN-13: 9780198834359
- ISBN-10: 0198834357
- Artikelnr.: 53446546
Dr Paul Farquhar-Smith, MA, MB, BChirFRCA, PhD, FFPMRCA, FFICM, is at present a Consultant in Pain Medicine and Anaesthesia at The Royal Marsden NHS Foundation Trust in London, UK. He specialises in pain in cancer patients and survivors (post-surgical chronic pain, chemotherapy induced neuropathy), and anaesthesia for breast and reconstructive surgery. Dr Pierre Beaulieu is at present a Professor of Anesthesiology and Pharmacology at Université de Montréal in Canada. He specialises in the pharmacology and neurobiology of pain, the use of cannabinoids for treatment of pain, and in local anaesthetics Dr Siân Jaggar is at present a Consultant in Anaesthesia at Royal Brompton & Harefield NHS Foundation Trust in London, UK. She specialises in adult and paediatric cardiothoracic anaesthesia and pain relief. She has a particular interest in education as a tool to enhance understanding between different working groups. She is the Royal College deputy regional advisor for the North West Thames region and the lead for less than full time trainees in this region.
* Section 1: Historical
* 1: JAW (Tony) Wildsmith: Local anaesthetic substitutes for cocaine
* 2: Ben M. Thomas: Innovative concepts in pain management
* 3: Sebastian Brandner and Brigitta Brandner: Explaining reflex
sympathetic dystrophy
* 4: Alain Eschalier and Christophe Mallet: The rediscovery of
paracetamol
* 5: Fabrizio Benedetti: The pharmacology of placebos
* 6: Jean-Sébastien Walczak: Understanding the responsiveness of
c-fibres
* 7: Tony Dickenson: A new theory of pain
* 8: Manon Choinière and Gabriella Pagé: Three determinants of pain
* 9: Guy Rousseau: Purinergic nerves: a new type of nerve
* 10: Jeffrey S. Mogil: Genetic differences in opiate receptors
* 11: Pierre Rainville: Endogenous opioids in placebo-induced analgesia
* 12: Éric Troncy: Ethical pain experimentation in conscious animals
* 13: Argyro Fassoulaki: Local anaesthetic creams
* 14: Cathy Price: The backpain revolution
* 15: Pierre Sirois and Pedro D'orléans-Juste: The mechanism of aspirin
* 16: Yasser Al Omran and Qasim Aziz: Mechanisms of visceral pain in
IBS
* 17: Philippe Richebé and Cyril Rivat: The effects of morphine on the
central nervous system
* 18: Joan Hester: Opiods in palliative care
* 19: Tony Dickenson: Endogenous opioids in the central nervous system
* 20: Craig W. Steven: Spinal opioid analgesia in the rat
* Section 2: Firsts
* 21: Paul Farquhar-Smith: The key role of NGF in inflammatory pain
processing
* 22: Elizabeth J. Bradbury and Nicholas D. James: Mapping of
neurotrophin receptors on adult sensory neurons
* 23: Stephen R. Humble: Plasticity in somatic receptive fields after
nerve injury
* 24: Amanda Klein and Matthias Ringkamp: Peripheral neural mechanisms
of cutaneous hyperalgesia and heat pain
* 25: Mary E. Abood and Thomas Gamage: The Cloning and Characterization
of CB1
* 26: Mark F. Bird and David Lambert: Deorphanisation of ORL-1/LC132 by
reverse pharmacology in two landmark studies
* 27: Istvan Nagy: The capsaicin receptor
* 28: Istvan Nagy: Vanilloid receptor 1 in inflammatory thermal
hyperalgesia
* 29: Pierre Rainville: A signature of pain in the brain
* 30: John Schutzer-Weissmann: Cytokines as central to peripheral
sensitisation and hyperalgesia
* 31: Claudia Sommer: Endogenous opioids mediate stress-induced
analgesia
* 32: Ke Ren Ronald Dubner: The first crystal structure of an iGluR
ligand-binding core
* 33: Andrea Hohmann: Control of pain initiation by endogenous
cannabinoids
* 34: Julie Desroches: Peripheral Analgesia involves Cannabinoid
Receptors
* 35: Marzia Malcangio: Glia: a new pain target
* 36: Bradley Kerr and Muhammad Saad Yousuf: The challenges of animal
models of pain
* 37: Philippe Sarret: Mechanisms of bone cancer pain
* 38: Roger Knaggs: Molecular Structure of the Mu-Opioid Receptor
* 39: Serge Marchand: Milestone Effect of DNIC in our Understanding of
Pain
* 40: Sheila Black: Original description of central sensitisation
* 41: Lesley Bromley: Molecular basis for Placebo effect
* Section 3: Science
* 42: Robert D. Searle: Early discussions on a mechanistic approach to
pain
* 43: Alfredo Ribeiro and Da Silva Claire Magnussen: Plasticity: a key
concept in pain
* 44: Enrique Collantes: The importance of descending modulatory pain
systems
* 45: Helen Laycock: Nocebo and its importance in clinical practice
* 46: Pierre Beaulieu: Mechanisms of Action of Acetaminophen for Pain
Treatment
* 47: Juergen Sandkuehler: Making the link from central sensitization
to clinical pain
* Section 4: Clinical
* 48: Vicky Tidman: Proof of concept: epidural morphine
* 49: Mike Shipley: The Definition of Fibromyalgia
* 50: Suzanne Chapman: The advent of PCA for post operative analgesia
* 51: Matthew J. Allsop and Michael Bennett: Undertreatment of pain
with metastatic cancer
* 52: Alison Bliss: Faces scales in paediatric pain assessment
* 53: Stephan Schug: Epidural block and phantom limb pain
* 54: Giovambattista Zeppetella: Clarifying the concept of Breakthrough
pain
* Section 5: Mechanisms
* 55: Alison Bliss: Paediatric pain epidemiology
* 56: Peter Kamerman: Recognising the importance of HIV disease and
pain
* 57: Andrew N. Davies: Fast acting fentanyl for breakthrough pain
* 58: Paul Farquhar-Smith: The additive analgesia of adrenaline in
epidural blockade
* 59: Felicia Cox: What is the clinical relevance of the Likert scale
for pain
* 60: Jane Quinlan: Post operative pain: assessing the standards
* 61: Kirsty Bannister: Opioid induced hyperalgesia
* 62: Naomi Scott: CRPS epidemiology
* 63: Paul Farquhar-Smith: Seminal paper on epidemiology of cancer pain
* 64: Arun Bhaskar: Endoscopic ultrasound guided coeliac plexus block
* Section 6: Neuropathic
* 65: Nicholas D. James and Elizabeth J. Bradbury: Autotomy: an early
neuropathic pain model
* 66: Tudor Phillips: Risk factors for post amputation pain
* 67: Matthew Brown: Chronic constriction injury (CCI) model of
neuropathic pain
* 68: Mick G. Serpell: Antineuropathic medication combination therapy
* 69: Rajesh Gupta: RCT evidence for gabapentin in post herpetic
neuralgia
* 70: Turo J. Nurmikko: Identification of the target of gabapentinoid
action in neuropathic pain
* 71: Matthew Brown: Recognition of the importance of Neuropathic pain
epidemiology
* 72: Abdelghani Mowafak: Botox analgesia for neuropathic pain
* 73: Sibtain Anwar: DNIC and prediction of chronic post surgical pain
* 74: Richard M. Langford: Pregabalin in the reduction of chronic post
knee surgery chronic pain
* 75: Toby Newton John: Multidisciplinary Cognitive Behavioural
Treatment for Chronic Pain
* 76: Rakesh Jain: Disability in Chronic Low Back Pain
* Section 7: Psychosocial
* 77: Amanda Williams: The Understanding of Social Effects in Pain
* Section 8: Genetics
* 78: Bhagat Singh. Alban Latremoliere, and Michael Costigan:
Congenital insensitivity to pain
* 79: Ingolf Cascorbi: Polymorphic CYP2D6 as the Responsible Enzyme of
Activation
* 80: Matthew Hamilton: COMT genotypes in pain responses
* 81: Bradley J. Kerr: The link between NaV1.7 mutation and
erythromelalgia
* 82: Fausto Morell-Ducos: COMT and morphine use in cancer pain
* 83: Roman Cregg and Biloshytsky Vadym: Pioneering use of gene therapy
for pain
* 1: JAW (Tony) Wildsmith: Local anaesthetic substitutes for cocaine
* 2: Ben M. Thomas: Innovative concepts in pain management
* 3: Sebastian Brandner and Brigitta Brandner: Explaining reflex
sympathetic dystrophy
* 4: Alain Eschalier and Christophe Mallet: The rediscovery of
paracetamol
* 5: Fabrizio Benedetti: The pharmacology of placebos
* 6: Jean-Sébastien Walczak: Understanding the responsiveness of
c-fibres
* 7: Tony Dickenson: A new theory of pain
* 8: Manon Choinière and Gabriella Pagé: Three determinants of pain
* 9: Guy Rousseau: Purinergic nerves: a new type of nerve
* 10: Jeffrey S. Mogil: Genetic differences in opiate receptors
* 11: Pierre Rainville: Endogenous opioids in placebo-induced analgesia
* 12: Éric Troncy: Ethical pain experimentation in conscious animals
* 13: Argyro Fassoulaki: Local anaesthetic creams
* 14: Cathy Price: The backpain revolution
* 15: Pierre Sirois and Pedro D'orléans-Juste: The mechanism of aspirin
* 16: Yasser Al Omran and Qasim Aziz: Mechanisms of visceral pain in
IBS
* 17: Philippe Richebé and Cyril Rivat: The effects of morphine on the
central nervous system
* 18: Joan Hester: Opiods in palliative care
* 19: Tony Dickenson: Endogenous opioids in the central nervous system
* 20: Craig W. Steven: Spinal opioid analgesia in the rat
* Section 2: Firsts
* 21: Paul Farquhar-Smith: The key role of NGF in inflammatory pain
processing
* 22: Elizabeth J. Bradbury and Nicholas D. James: Mapping of
neurotrophin receptors on adult sensory neurons
* 23: Stephen R. Humble: Plasticity in somatic receptive fields after
nerve injury
* 24: Amanda Klein and Matthias Ringkamp: Peripheral neural mechanisms
of cutaneous hyperalgesia and heat pain
* 25: Mary E. Abood and Thomas Gamage: The Cloning and Characterization
of CB1
* 26: Mark F. Bird and David Lambert: Deorphanisation of ORL-1/LC132 by
reverse pharmacology in two landmark studies
* 27: Istvan Nagy: The capsaicin receptor
* 28: Istvan Nagy: Vanilloid receptor 1 in inflammatory thermal
hyperalgesia
* 29: Pierre Rainville: A signature of pain in the brain
* 30: John Schutzer-Weissmann: Cytokines as central to peripheral
sensitisation and hyperalgesia
* 31: Claudia Sommer: Endogenous opioids mediate stress-induced
analgesia
* 32: Ke Ren Ronald Dubner: The first crystal structure of an iGluR
ligand-binding core
* 33: Andrea Hohmann: Control of pain initiation by endogenous
cannabinoids
* 34: Julie Desroches: Peripheral Analgesia involves Cannabinoid
Receptors
* 35: Marzia Malcangio: Glia: a new pain target
* 36: Bradley Kerr and Muhammad Saad Yousuf: The challenges of animal
models of pain
* 37: Philippe Sarret: Mechanisms of bone cancer pain
* 38: Roger Knaggs: Molecular Structure of the Mu-Opioid Receptor
* 39: Serge Marchand: Milestone Effect of DNIC in our Understanding of
Pain
* 40: Sheila Black: Original description of central sensitisation
* 41: Lesley Bromley: Molecular basis for Placebo effect
* Section 3: Science
* 42: Robert D. Searle: Early discussions on a mechanistic approach to
pain
* 43: Alfredo Ribeiro and Da Silva Claire Magnussen: Plasticity: a key
concept in pain
* 44: Enrique Collantes: The importance of descending modulatory pain
systems
* 45: Helen Laycock: Nocebo and its importance in clinical practice
* 46: Pierre Beaulieu: Mechanisms of Action of Acetaminophen for Pain
Treatment
* 47: Juergen Sandkuehler: Making the link from central sensitization
to clinical pain
* Section 4: Clinical
* 48: Vicky Tidman: Proof of concept: epidural morphine
* 49: Mike Shipley: The Definition of Fibromyalgia
* 50: Suzanne Chapman: The advent of PCA for post operative analgesia
* 51: Matthew J. Allsop and Michael Bennett: Undertreatment of pain
with metastatic cancer
* 52: Alison Bliss: Faces scales in paediatric pain assessment
* 53: Stephan Schug: Epidural block and phantom limb pain
* 54: Giovambattista Zeppetella: Clarifying the concept of Breakthrough
pain
* Section 5: Mechanisms
* 55: Alison Bliss: Paediatric pain epidemiology
* 56: Peter Kamerman: Recognising the importance of HIV disease and
pain
* 57: Andrew N. Davies: Fast acting fentanyl for breakthrough pain
* 58: Paul Farquhar-Smith: The additive analgesia of adrenaline in
epidural blockade
* 59: Felicia Cox: What is the clinical relevance of the Likert scale
for pain
* 60: Jane Quinlan: Post operative pain: assessing the standards
* 61: Kirsty Bannister: Opioid induced hyperalgesia
* 62: Naomi Scott: CRPS epidemiology
* 63: Paul Farquhar-Smith: Seminal paper on epidemiology of cancer pain
* 64: Arun Bhaskar: Endoscopic ultrasound guided coeliac plexus block
* Section 6: Neuropathic
* 65: Nicholas D. James and Elizabeth J. Bradbury: Autotomy: an early
neuropathic pain model
* 66: Tudor Phillips: Risk factors for post amputation pain
* 67: Matthew Brown: Chronic constriction injury (CCI) model of
neuropathic pain
* 68: Mick G. Serpell: Antineuropathic medication combination therapy
* 69: Rajesh Gupta: RCT evidence for gabapentin in post herpetic
neuralgia
* 70: Turo J. Nurmikko: Identification of the target of gabapentinoid
action in neuropathic pain
* 71: Matthew Brown: Recognition of the importance of Neuropathic pain
epidemiology
* 72: Abdelghani Mowafak: Botox analgesia for neuropathic pain
* 73: Sibtain Anwar: DNIC and prediction of chronic post surgical pain
* 74: Richard M. Langford: Pregabalin in the reduction of chronic post
knee surgery chronic pain
* 75: Toby Newton John: Multidisciplinary Cognitive Behavioural
Treatment for Chronic Pain
* 76: Rakesh Jain: Disability in Chronic Low Back Pain
* Section 7: Psychosocial
* 77: Amanda Williams: The Understanding of Social Effects in Pain
* Section 8: Genetics
* 78: Bhagat Singh. Alban Latremoliere, and Michael Costigan:
Congenital insensitivity to pain
* 79: Ingolf Cascorbi: Polymorphic CYP2D6 as the Responsible Enzyme of
Activation
* 80: Matthew Hamilton: COMT genotypes in pain responses
* 81: Bradley J. Kerr: The link between NaV1.7 mutation and
erythromelalgia
* 82: Fausto Morell-Ducos: COMT and morphine use in cancer pain
* 83: Roman Cregg and Biloshytsky Vadym: Pioneering use of gene therapy
for pain
* Section 1: Historical
* 1: JAW (Tony) Wildsmith: Local anaesthetic substitutes for cocaine
* 2: Ben M. Thomas: Innovative concepts in pain management
* 3: Sebastian Brandner and Brigitta Brandner: Explaining reflex
sympathetic dystrophy
* 4: Alain Eschalier and Christophe Mallet: The rediscovery of
paracetamol
* 5: Fabrizio Benedetti: The pharmacology of placebos
* 6: Jean-Sébastien Walczak: Understanding the responsiveness of
c-fibres
* 7: Tony Dickenson: A new theory of pain
* 8: Manon Choinière and Gabriella Pagé: Three determinants of pain
* 9: Guy Rousseau: Purinergic nerves: a new type of nerve
* 10: Jeffrey S. Mogil: Genetic differences in opiate receptors
* 11: Pierre Rainville: Endogenous opioids in placebo-induced analgesia
* 12: Éric Troncy: Ethical pain experimentation in conscious animals
* 13: Argyro Fassoulaki: Local anaesthetic creams
* 14: Cathy Price: The backpain revolution
* 15: Pierre Sirois and Pedro D'orléans-Juste: The mechanism of aspirin
* 16: Yasser Al Omran and Qasim Aziz: Mechanisms of visceral pain in
IBS
* 17: Philippe Richebé and Cyril Rivat: The effects of morphine on the
central nervous system
* 18: Joan Hester: Opiods in palliative care
* 19: Tony Dickenson: Endogenous opioids in the central nervous system
* 20: Craig W. Steven: Spinal opioid analgesia in the rat
* Section 2: Firsts
* 21: Paul Farquhar-Smith: The key role of NGF in inflammatory pain
processing
* 22: Elizabeth J. Bradbury and Nicholas D. James: Mapping of
neurotrophin receptors on adult sensory neurons
* 23: Stephen R. Humble: Plasticity in somatic receptive fields after
nerve injury
* 24: Amanda Klein and Matthias Ringkamp: Peripheral neural mechanisms
of cutaneous hyperalgesia and heat pain
* 25: Mary E. Abood and Thomas Gamage: The Cloning and Characterization
of CB1
* 26: Mark F. Bird and David Lambert: Deorphanisation of ORL-1/LC132 by
reverse pharmacology in two landmark studies
* 27: Istvan Nagy: The capsaicin receptor
* 28: Istvan Nagy: Vanilloid receptor 1 in inflammatory thermal
hyperalgesia
* 29: Pierre Rainville: A signature of pain in the brain
* 30: John Schutzer-Weissmann: Cytokines as central to peripheral
sensitisation and hyperalgesia
* 31: Claudia Sommer: Endogenous opioids mediate stress-induced
analgesia
* 32: Ke Ren Ronald Dubner: The first crystal structure of an iGluR
ligand-binding core
* 33: Andrea Hohmann: Control of pain initiation by endogenous
cannabinoids
* 34: Julie Desroches: Peripheral Analgesia involves Cannabinoid
Receptors
* 35: Marzia Malcangio: Glia: a new pain target
* 36: Bradley Kerr and Muhammad Saad Yousuf: The challenges of animal
models of pain
* 37: Philippe Sarret: Mechanisms of bone cancer pain
* 38: Roger Knaggs: Molecular Structure of the Mu-Opioid Receptor
* 39: Serge Marchand: Milestone Effect of DNIC in our Understanding of
Pain
* 40: Sheila Black: Original description of central sensitisation
* 41: Lesley Bromley: Molecular basis for Placebo effect
* Section 3: Science
* 42: Robert D. Searle: Early discussions on a mechanistic approach to
pain
* 43: Alfredo Ribeiro and Da Silva Claire Magnussen: Plasticity: a key
concept in pain
* 44: Enrique Collantes: The importance of descending modulatory pain
systems
* 45: Helen Laycock: Nocebo and its importance in clinical practice
* 46: Pierre Beaulieu: Mechanisms of Action of Acetaminophen for Pain
Treatment
* 47: Juergen Sandkuehler: Making the link from central sensitization
to clinical pain
* Section 4: Clinical
* 48: Vicky Tidman: Proof of concept: epidural morphine
* 49: Mike Shipley: The Definition of Fibromyalgia
* 50: Suzanne Chapman: The advent of PCA for post operative analgesia
* 51: Matthew J. Allsop and Michael Bennett: Undertreatment of pain
with metastatic cancer
* 52: Alison Bliss: Faces scales in paediatric pain assessment
* 53: Stephan Schug: Epidural block and phantom limb pain
* 54: Giovambattista Zeppetella: Clarifying the concept of Breakthrough
pain
* Section 5: Mechanisms
* 55: Alison Bliss: Paediatric pain epidemiology
* 56: Peter Kamerman: Recognising the importance of HIV disease and
pain
* 57: Andrew N. Davies: Fast acting fentanyl for breakthrough pain
* 58: Paul Farquhar-Smith: The additive analgesia of adrenaline in
epidural blockade
* 59: Felicia Cox: What is the clinical relevance of the Likert scale
for pain
* 60: Jane Quinlan: Post operative pain: assessing the standards
* 61: Kirsty Bannister: Opioid induced hyperalgesia
* 62: Naomi Scott: CRPS epidemiology
* 63: Paul Farquhar-Smith: Seminal paper on epidemiology of cancer pain
* 64: Arun Bhaskar: Endoscopic ultrasound guided coeliac plexus block
* Section 6: Neuropathic
* 65: Nicholas D. James and Elizabeth J. Bradbury: Autotomy: an early
neuropathic pain model
* 66: Tudor Phillips: Risk factors for post amputation pain
* 67: Matthew Brown: Chronic constriction injury (CCI) model of
neuropathic pain
* 68: Mick G. Serpell: Antineuropathic medication combination therapy
* 69: Rajesh Gupta: RCT evidence for gabapentin in post herpetic
neuralgia
* 70: Turo J. Nurmikko: Identification of the target of gabapentinoid
action in neuropathic pain
* 71: Matthew Brown: Recognition of the importance of Neuropathic pain
epidemiology
* 72: Abdelghani Mowafak: Botox analgesia for neuropathic pain
* 73: Sibtain Anwar: DNIC and prediction of chronic post surgical pain
* 74: Richard M. Langford: Pregabalin in the reduction of chronic post
knee surgery chronic pain
* 75: Toby Newton John: Multidisciplinary Cognitive Behavioural
Treatment for Chronic Pain
* 76: Rakesh Jain: Disability in Chronic Low Back Pain
* Section 7: Psychosocial
* 77: Amanda Williams: The Understanding of Social Effects in Pain
* Section 8: Genetics
* 78: Bhagat Singh. Alban Latremoliere, and Michael Costigan:
Congenital insensitivity to pain
* 79: Ingolf Cascorbi: Polymorphic CYP2D6 as the Responsible Enzyme of
Activation
* 80: Matthew Hamilton: COMT genotypes in pain responses
* 81: Bradley J. Kerr: The link between NaV1.7 mutation and
erythromelalgia
* 82: Fausto Morell-Ducos: COMT and morphine use in cancer pain
* 83: Roman Cregg and Biloshytsky Vadym: Pioneering use of gene therapy
for pain
* 1: JAW (Tony) Wildsmith: Local anaesthetic substitutes for cocaine
* 2: Ben M. Thomas: Innovative concepts in pain management
* 3: Sebastian Brandner and Brigitta Brandner: Explaining reflex
sympathetic dystrophy
* 4: Alain Eschalier and Christophe Mallet: The rediscovery of
paracetamol
* 5: Fabrizio Benedetti: The pharmacology of placebos
* 6: Jean-Sébastien Walczak: Understanding the responsiveness of
c-fibres
* 7: Tony Dickenson: A new theory of pain
* 8: Manon Choinière and Gabriella Pagé: Three determinants of pain
* 9: Guy Rousseau: Purinergic nerves: a new type of nerve
* 10: Jeffrey S. Mogil: Genetic differences in opiate receptors
* 11: Pierre Rainville: Endogenous opioids in placebo-induced analgesia
* 12: Éric Troncy: Ethical pain experimentation in conscious animals
* 13: Argyro Fassoulaki: Local anaesthetic creams
* 14: Cathy Price: The backpain revolution
* 15: Pierre Sirois and Pedro D'orléans-Juste: The mechanism of aspirin
* 16: Yasser Al Omran and Qasim Aziz: Mechanisms of visceral pain in
IBS
* 17: Philippe Richebé and Cyril Rivat: The effects of morphine on the
central nervous system
* 18: Joan Hester: Opiods in palliative care
* 19: Tony Dickenson: Endogenous opioids in the central nervous system
* 20: Craig W. Steven: Spinal opioid analgesia in the rat
* Section 2: Firsts
* 21: Paul Farquhar-Smith: The key role of NGF in inflammatory pain
processing
* 22: Elizabeth J. Bradbury and Nicholas D. James: Mapping of
neurotrophin receptors on adult sensory neurons
* 23: Stephen R. Humble: Plasticity in somatic receptive fields after
nerve injury
* 24: Amanda Klein and Matthias Ringkamp: Peripheral neural mechanisms
of cutaneous hyperalgesia and heat pain
* 25: Mary E. Abood and Thomas Gamage: The Cloning and Characterization
of CB1
* 26: Mark F. Bird and David Lambert: Deorphanisation of ORL-1/LC132 by
reverse pharmacology in two landmark studies
* 27: Istvan Nagy: The capsaicin receptor
* 28: Istvan Nagy: Vanilloid receptor 1 in inflammatory thermal
hyperalgesia
* 29: Pierre Rainville: A signature of pain in the brain
* 30: John Schutzer-Weissmann: Cytokines as central to peripheral
sensitisation and hyperalgesia
* 31: Claudia Sommer: Endogenous opioids mediate stress-induced
analgesia
* 32: Ke Ren Ronald Dubner: The first crystal structure of an iGluR
ligand-binding core
* 33: Andrea Hohmann: Control of pain initiation by endogenous
cannabinoids
* 34: Julie Desroches: Peripheral Analgesia involves Cannabinoid
Receptors
* 35: Marzia Malcangio: Glia: a new pain target
* 36: Bradley Kerr and Muhammad Saad Yousuf: The challenges of animal
models of pain
* 37: Philippe Sarret: Mechanisms of bone cancer pain
* 38: Roger Knaggs: Molecular Structure of the Mu-Opioid Receptor
* 39: Serge Marchand: Milestone Effect of DNIC in our Understanding of
Pain
* 40: Sheila Black: Original description of central sensitisation
* 41: Lesley Bromley: Molecular basis for Placebo effect
* Section 3: Science
* 42: Robert D. Searle: Early discussions on a mechanistic approach to
pain
* 43: Alfredo Ribeiro and Da Silva Claire Magnussen: Plasticity: a key
concept in pain
* 44: Enrique Collantes: The importance of descending modulatory pain
systems
* 45: Helen Laycock: Nocebo and its importance in clinical practice
* 46: Pierre Beaulieu: Mechanisms of Action of Acetaminophen for Pain
Treatment
* 47: Juergen Sandkuehler: Making the link from central sensitization
to clinical pain
* Section 4: Clinical
* 48: Vicky Tidman: Proof of concept: epidural morphine
* 49: Mike Shipley: The Definition of Fibromyalgia
* 50: Suzanne Chapman: The advent of PCA for post operative analgesia
* 51: Matthew J. Allsop and Michael Bennett: Undertreatment of pain
with metastatic cancer
* 52: Alison Bliss: Faces scales in paediatric pain assessment
* 53: Stephan Schug: Epidural block and phantom limb pain
* 54: Giovambattista Zeppetella: Clarifying the concept of Breakthrough
pain
* Section 5: Mechanisms
* 55: Alison Bliss: Paediatric pain epidemiology
* 56: Peter Kamerman: Recognising the importance of HIV disease and
pain
* 57: Andrew N. Davies: Fast acting fentanyl for breakthrough pain
* 58: Paul Farquhar-Smith: The additive analgesia of adrenaline in
epidural blockade
* 59: Felicia Cox: What is the clinical relevance of the Likert scale
for pain
* 60: Jane Quinlan: Post operative pain: assessing the standards
* 61: Kirsty Bannister: Opioid induced hyperalgesia
* 62: Naomi Scott: CRPS epidemiology
* 63: Paul Farquhar-Smith: Seminal paper on epidemiology of cancer pain
* 64: Arun Bhaskar: Endoscopic ultrasound guided coeliac plexus block
* Section 6: Neuropathic
* 65: Nicholas D. James and Elizabeth J. Bradbury: Autotomy: an early
neuropathic pain model
* 66: Tudor Phillips: Risk factors for post amputation pain
* 67: Matthew Brown: Chronic constriction injury (CCI) model of
neuropathic pain
* 68: Mick G. Serpell: Antineuropathic medication combination therapy
* 69: Rajesh Gupta: RCT evidence for gabapentin in post herpetic
neuralgia
* 70: Turo J. Nurmikko: Identification of the target of gabapentinoid
action in neuropathic pain
* 71: Matthew Brown: Recognition of the importance of Neuropathic pain
epidemiology
* 72: Abdelghani Mowafak: Botox analgesia for neuropathic pain
* 73: Sibtain Anwar: DNIC and prediction of chronic post surgical pain
* 74: Richard M. Langford: Pregabalin in the reduction of chronic post
knee surgery chronic pain
* 75: Toby Newton John: Multidisciplinary Cognitive Behavioural
Treatment for Chronic Pain
* 76: Rakesh Jain: Disability in Chronic Low Back Pain
* Section 7: Psychosocial
* 77: Amanda Williams: The Understanding of Social Effects in Pain
* Section 8: Genetics
* 78: Bhagat Singh. Alban Latremoliere, and Michael Costigan:
Congenital insensitivity to pain
* 79: Ingolf Cascorbi: Polymorphic CYP2D6 as the Responsible Enzyme of
Activation
* 80: Matthew Hamilton: COMT genotypes in pain responses
* 81: Bradley J. Kerr: The link between NaV1.7 mutation and
erythromelalgia
* 82: Fausto Morell-Ducos: COMT and morphine use in cancer pain
* 83: Roman Cregg and Biloshytsky Vadym: Pioneering use of gene therapy
for pain