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The efficacy of Cassia tora leaf meal as an ingredient in the diet of the African catfish (Clarias gariepinus) fingerlings of mean weight 2.17±0.01g was evaluated over 63-days growth period. Five experimental diets were formulated at 0%, 3%, 6%, 9%, and 12% inclusion level of the leaf meal. These revealed that the leaf meal could serve as protein supplement. The results of phytochemical test analyzed revealed that the leaf contains anti- nutritional factors such as alkaloids, tannins, steroids, saponins and flavonoids. The growth indices for diet I (control) revealed highest mean weight gain, weekly weight gain, specific growth rate and percentage weight gain. These were significantly (P0.05) higher than the values for other dietary treatments.