The fourth edition of 'Lehninger Principles of Biochemistry' stays true to the vision of its predecessors while embracing the advances made in biochemical research since the previous edition. As always, the book presents the fundamentals of biochemistry through selected topics, and emphasizes the most important recent developments and applications without abandoning the classical core of the subject. The new edition has been carefully streamlined to reduce the length of the book without compromizing content. As with previous editions, it emphasizes clear prose and student-friendly explanations to optimize student comprehension. It also contains a groundbreaking new treatment of metabolic regulation, up-to-date coverage of DNA-based information technologies, many new applications and problems, and a new graphical style for enzyme reaction mechanisms, including step-by-step annotations that clarify the concepts and chemical logic of enzymatic reactions. Lecturer supplements include: Instructor's Resource CD-ROM with Test Bank, Printed Test Bank and a set of 150 Overhead Transparencies.For students a Study Guide and Solutions Manual is available which includes discussion questions, a self-test and a Cellular Metabolic Map, as well as a Lecture Notebook containing the essential diagrams and reaction equations in the text. The textbook's dedicated website www.whfreeman.com/lehninger offers numerous features including PowerPoint images, animated mechanisms and living graphs.
Contents:
The Foundations of BiochemistryPART I: STRUCTURE AND CATALYSISWaterAmino Acids and ProteinsThe Three-Dimensional Structure of ProteinsProtein FunctionEnzymesCarbohydrates and GlycoconjugatesNucleotides and Nucleic AcidsDNA-Based Information TechnologiesLipidsBiological Membranes and TransportBiosignalingPART II: BIOENERGETICS AND METABOLISMPrinciples of BioenergeticsGlycolysis, Gluconeogenesis, and the Pentose Phosphate PathwayPrinciples of Regulation, Illustrated with the Metabolism of Glucose and GlycogenThe Citric Acid CycleOxidation of Fatty AcidsAmino Acid Oxidation and the Production of UreaOxidative Phosphorylation and PhotophosphorylationCarbohydrate Biosynthesis in Plants and BacteriaLipid BiosynthesisBiosynthesis of Amino Acids, Nucleotides and Related MoleculesIntegration and Hormonal Regulation of Mammalian MetabolismPART III: INFORMATION PATHWAYSGenes and ChromosomesDNA Metabolism RNA MetabolismProtein MetabolismRegulation of Gene Expression
Contents:
The Foundations of BiochemistryPART I: STRUCTURE AND CATALYSISWaterAmino Acids and ProteinsThe Three-Dimensional Structure of ProteinsProtein FunctionEnzymesCarbohydrates and GlycoconjugatesNucleotides and Nucleic AcidsDNA-Based Information TechnologiesLipidsBiological Membranes and TransportBiosignalingPART II: BIOENERGETICS AND METABOLISMPrinciples of BioenergeticsGlycolysis, Gluconeogenesis, and the Pentose Phosphate PathwayPrinciples of Regulation, Illustrated with the Metabolism of Glucose and GlycogenThe Citric Acid CycleOxidation of Fatty AcidsAmino Acid Oxidation and the Production of UreaOxidative Phosphorylation and PhotophosphorylationCarbohydrate Biosynthesis in Plants and BacteriaLipid BiosynthesisBiosynthesis of Amino Acids, Nucleotides and Related MoleculesIntegration and Hormonal Regulation of Mammalian MetabolismPART III: INFORMATION PATHWAYSGenes and ChromosomesDNA Metabolism RNA MetabolismProtein MetabolismRegulation of Gene Expression