Amir Zaidi

Leishmaniasis and the role of Iron

• Broschiertes Buch

Produktbeschreibung

The unicellular kinetoplastid protozoan parasites of genus Leishmania are the causative agents of complex neglected diseases called leishmaniasis and continue to be a significant health concern globally. Chapter 1 provide a brief overview of leishmaniasis and outline the number of drugs available for the treatment along with the possible targeted pathway in Leishmania parasite. The aim of chapter 2 is to provide an update on the current knowledge about iron acquisition and usage by Leishmania species. For the parasite survival and virulence, iron as metal ion plays a crucial role in many facets of cellular metabolism as a cofactor of several enzymes. Iron acquisition is essential for the survival of parasites. Since iron plays central roles in the host's response and parasite metabolism, a comprehensive understanding of the iron metabolism is beneficial to identify potential viable therapeutic opportunities against leishmaniasis.

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Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Seitenzahl: 64
• Erscheinungstermin: 11. August 2017
• Englisch
• Abmessung: 220mm x 150mm x 4mm
• Gewicht: 113g
• ISBN-13: 9786202005258
• ISBN-10: 6202005254
• Artikelnr.: 49054876

Autorenporträt

Amir Zaidi, M.Sc. Biochemistry from Jamia Hamdard, New Delhi and Ph.D.(Biochemistry) from University of Calcutta. He studied the Fe-S cluster assembly machinery of model pathogen Leishmania donovani which causes visceral leishmaniasis.