The use of social media has become part and parcel of our lives. What then can we benefit from social media to help in providing solutions to some of challenges that we face such as in health? Do we fully understand social media and its interactive and dialogic nature that enhances feedback? Through exploring social media in HIV and AIDS Communication, the book provides insights on specific appropriateness of different social media platforms that enhances content creation and consumption with specific preferences in social media platforms while matching the audience gratifications such as entertainment so as to capture attention and attract the audiences to HIV and AIDS information.