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Liposome are small vesicle of spherical shape that can be produced from cholesterol, nontoxic surfactants, sphingolipids, glycolipids, long chain fatty acid and even membrane protein . Liposome is the drug carrier loaded with great variety of molecule such as small drug molecules, proteins nucleotides and even plasmids. The discovery of liposome or lipid vesicle emerged from self forming enclosed lipid bilayer upon hydration; liposome drug delivery system have played a significant role in formation of potent drug to improve therapeutics. Recently the liposome formulations are targeted to reduce toxicity and increase accumulation at the target site. The new developments in this field are the specific binding properties of a drug carrying liposome to target cell such as tumour cell.