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Introduction: Hyperthermia as an Oncological Therapy Concept - Molecular and immunological effects of hyperthermia on tumour progression and metastasis - General activation of the immune system - Temperature increase above 41C leading to death of tumour cells - Synergy from hyperthermia and chemotherapy and/or radiotherapy - Systemic effects of regional, deep hyperthermia - Physical and technical principles of regional, deep hyperthermia - Definition of Terms - Thermal Dose - Method of regional deep hyperthermia in general and especially in oncothermia - The significance of regional deep hyperthermia within drug tumour therapy - Matched-pair analysis of patients with hepatic metastatic carcinoma of the colon (chemotherapy on the liver with and without regional deep hyperthermia) ¿ Problem Group of patients ¿ Hyperthermia ¿ Chemotherapy ¿ Results - Discussion: Integration of regional deep hyperthermia with oncological treatment concepts ¿ Summary - Bibliography - Appendix (Data sheet)