Locating a manufacturing firm is a challenging task for most managers/owners due to its strategic nature. The significance of selecting perfect locations become important as the success or failure of a firm depends on its location. However, limited information is available on the relative importance of various site selection and operation strategic factors for firms in this sector when making investment and strategic decisions in spite of the continued growth of the industry. Hence, this study determines the importance and the possible relationships between the location decisions factors that influence operations strategy and how these affect the business performance of firms in the manufacturing industry.