Lipids are the second component of marine fish diets, the main source of PUFAs and plays a pivotal role in several physiological processes which are essential molecules for maintaining cellular membrane integrity, the synthesis of eicosanoids and steroid hormones, and the absorption of fat-soluble vitamins. Which makes us provide information on the dietary requirement of n-3 LC-PUFA, the specific importance of DHA, EPA and ARA, the practical applications for addition , The supply of n-3 LC-PUFA for fish diets to determine the optimum dietary level of n-3 LC-PUFA for growth performance, antioxidant status and Implication of LC-PUFA supplementation for Meagre (Argyrosomus regius) (Asso, 1801) larvae .