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Lorenzo di Piero de' Medici was the ruler of Florence from 1513 to his death from syphilis in 1519. He was also Duke of Urbino from 1516 to 1519. Born in Florence, he was a son of Piero di Lorenzo de' Medici and Alfonsina Orsini. His paternal grandparents were Lorenzo the Magnificent and Clarice Orsini. His maternal grandparents were Roberto Orsini, Conte Tagliacozzo and Catherine San Severino. Niccolò Machiavelli dedicated The Prince to Lorenzo to inform him of tactics to use in unifying Italy, though the entire intent behind this dedication is shrouded in mystery. His uncle, the Medici, Pope…mehr

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Lorenzo di Piero de' Medici was the ruler of Florence from 1513 to his death from syphilis in 1519. He was also Duke of Urbino from 1516 to 1519. Born in Florence, he was a son of Piero di Lorenzo de' Medici and Alfonsina Orsini. His paternal grandparents were Lorenzo the Magnificent and Clarice Orsini. His maternal grandparents were Roberto Orsini, Conte Tagliacozzo and Catherine San Severino. Niccolò Machiavelli dedicated The Prince to Lorenzo to inform him of tactics to use in unifying Italy, though the entire intent behind this dedication is shrouded in mystery. His uncle, the Medici, Pope Leo X, made "Lorenzino" duke of Urbino in 1516 at the age of 24. After the short reconquest by the former duke, Francesco Maria I della Rovere, Lorenzo was named commander of the 10,000 men sent to recapture it, but was wounded and retired to Tuscany