The exponential increases in neurodevelopmental disorders implicate both genetic causes and environmental factors. Flame-retardants, pesticides, plasticizers, and other every-day products contain chemicals shown to affect thyroid hormone signaling, which if disrupted can result in significant impairment to IQ. Across entire populations, such effects spell large-scale social and economic consequences.
The exponential increases in neurodevelopmental disorders implicate both genetic causes and environmental factors. Flame-retardants, pesticides, plasticizers, and other every-day products contain chemicals shown to affect thyroid hormone signaling, which if disrupted can result in significant impairment to IQ. Across entire populations, such effects spell large-scale social and economic consequences.
Barbara Demeneix is an internationally recognized expert on thyroid function and endocrine disruption. She is the author of more than 140 scientific publications, patents, and book chapters. Trained in the United Kingdom, France, Canada, and Germany, she currently serves as Professor of Comparative Physiology and Head of Department at the National History Museum in Paris, France.
Inhaltsangabe
* Contents * 1. Chemical Pollution and IQ Loss in Children: Learning from the Past * 2. Thyroid Hormone, Iodine, Selenium, and Mercury * 3. Thyroid Hormone and Brain Development: Bridging Environment to Gene Expression * 4. Thyroid Hormone Signalling as a Target of Multiple Pollutants * 5. Examples of Chemical Pollution Targeting Thyroid Hormone Action * 6. Mixtures and Low Doses: The Complexity of Risk Assessment * 7. Autism Spectrum Disorder, Attention Deficit/Hyperactivity Disorder, Congenital Hypothyroidism: The Case for Gene x Environment Interactions * 8. What Can Be Done by Individuals, Associations and Governments: Time to End the Pied Piper Scenario
* Contents * 1. Chemical Pollution and IQ Loss in Children: Learning from the Past * 2. Thyroid Hormone, Iodine, Selenium, and Mercury * 3. Thyroid Hormone and Brain Development: Bridging Environment to Gene Expression * 4. Thyroid Hormone Signalling as a Target of Multiple Pollutants * 5. Examples of Chemical Pollution Targeting Thyroid Hormone Action * 6. Mixtures and Low Doses: The Complexity of Risk Assessment * 7. Autism Spectrum Disorder, Attention Deficit/Hyperactivity Disorder, Congenital Hypothyroidism: The Case for Gene x Environment Interactions * 8. What Can Be Done by Individuals, Associations and Governments: Time to End the Pied Piper Scenario
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