High Quality Content by WIKIPEDIA articles! Luis Colón de Toledo, 1st Duke of la Vega, 2nd Duke of Veragua, 2nd Marquis of Jamaica and 3rd Admiral of the Indies (Santo Domingo, 1519/1520/1522 January 29, 1572), was the first son of Diego Colón (making him the grandson of famous explorer Christopher Columbus) and wife María de Toledo y Rojas. After his father's death, a compromise was reached in 1536 in which he was named 3rd Admiral of the Indies and renounced all other rights for a perpetual annuity of 10,000 ducats, the island of Jamaica as a fief, an estate of 25 square leagues on the Isthmus of Panama, then called Veragua, and the titles of 2nd Duke of Veragua and 2nd Marquess of Jamaica and 1st Duke of la Vega.