This book presents a novel system design for lung cancer detection from CT images using machine learning method. Modern 3D imaging provides the opportunity for significant advancement in science and medicine,as higher resolution images is generated, and promises. Due to advances in computer aided diagnosis and continuous progress in the field of computerized medical image visualization there is need to develop Scientific imaging is one of the most important areas. There are many cancers, one of the most common of which is lung cancer. The patients of cancer is increasing every day. Lung cancer is the second most common cancer that causes death in both men and women.