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Pulmonary sequestration is a rare bronchopulmonary malformation.Aim: To clarify the clinico-biological aspects and management of pulmonary sequestration. Material and methods: We conducted a retrospective descriptive study of 16 observations of pulmonary sequestration managed in the pediatric surgery department of the Fattouma Bourguiba Hospital, Monastir.Results: Our series included 7 boys and 9 girls. The mean age was 30 months. Antenatal diagnosis was made in 8 cases. The clinical picture was dominated by respiratory symptoms in 13 cases. In the remaining three cases, the diagnosis was made incidentally during surgery. Imaging suggested the diagnosis in 7 patients. All children underwent surgery. Thoracoscopy was performed in 8 children, and conversion was performed in 3 patients. Removal was by sequestrectomy in the case of extra-lobar sequestration; lobectomy in the case of intra-lobar sequestration and in hybrid forms. All patients had a favourable outcome.Conclusion: Pulmonary sequestration can take on different aspects, sometimes leading to confusion.