High Quality Content by WIKIPEDIA articles! Machado-Joseph disease or Spinocerebellar ataxia type 3 is an extremely rare hereditary ataxia, which means a lack of muscle control. It is caused by a certain mutation that results in degeneration of cells in the hindbrain. Some symptoms, such as clumsiness and rigidity, make MJD commonly mistaken for drunkenness and/or Parkinson's disease. Machado-Joseph disease is a type of spinocerebellar ataxia that causes ophthalmoplegia and mixed sensory and cerebellar ataxia. The disease was first identified in 1972. Unlike many other medical conditions, Machado-Joseph disease isn't named after researchers. It is named after two men who were the patriarchs of the families in which the condition was initially described.
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