Stojanka Petru¿i¿

Macro and Micro Forms of Thermosensitive Hydrogels

Development, Characterization and Controlled Drug Release

• Broschiertes Buch

Produktbeschreibung

This book reports on a study in the macro and micro forms of thermosensitive hydrogels based on poly(N-isopropylacrylamide) (PNIPAAm) that are intended for use in textile-based applications in a controlled release of drugs via a transdermal route. A synthetic polymer PNIPAAm was combined in both the linear and crosslinked form with a natural polysaccharide alginate to form thermosensitive hydrogel films and microbeads of semi- and full-interpenetrating polymer network structures. A further form of thermosensitive hydrogel microbeads was obtained by the modification of PNIPAAm network in the presence of maleic anhydride as a comonomer. The study underlines the advantages of functionalized over pure PNIPAAm hydrogels in terms of their thermal, swelling, mechanical, morphological, and drug releasing properties. The presented research constitutes a valuable starting point in development of a smart textile patch that has properties to release the drugs at a temperature-controlled rate.

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Produktdetails

• Verlag: LAP LAMBERT Academic Publishing
• Seitenzahl: 332
• Erscheinungstermin: 29. August 2013
• Englisch
• Abmessung: 220mm x 150mm x 20mm
• Gewicht: 512g
• ISBN-13: 9783659444654
• ISBN-10: 3659444650
• Artikelnr.: 62750092

Autorenporträt

Stojanka Petrüi¿ graduated from the University of Belgrade, Faculty of Technology and Metallurgy, Serbia. She was awarded a double Ph.D. degree from Lille University of Science and Technology, France and the University of Belgrade, Serbia. She is currently employed as a postdoctoral researcher at ENSAIT in Roubaix, France.