Macromolecular Protein Complexes III: Structure and Function

Herausgegeben:Harris, J. Robin; Marles-Wright, Jon

• Gebundenes Buch

Produktbeschreibung

This book covers important topics such as the dynamic structure and function of the 26S proteasome, the DNA replication machine: structure and dynamic function and the structural organization and protein-protein interactions in the human adenovirus capsid, to mention but a few.

The 18 chapters included here, written by experts in their specific field, are at the forefront of scientific knowledge. The impressive integration of structural data from X-ray crystallography with that from cryo-electron microscopy is apparent throughout the book. In addition, functional aspects are also given a high priority.

Chapter 1 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Produktdetails

• Subcellular Biochemistry 96
• Verlag: Springer / Springer International Publishing / Springer, Berlin
• Artikelnr. des Verlages: 978-3-030-58970-7
• 1st ed. 2021
• Seitenzahl: 588
• Erscheinungstermin: 1. Dezember 2020
• Englisch
• Abmessung: 241mm x 160mm x 35mm
• Gewicht: 1146g
• ISBN-13: 9783030589707
• ISBN-10: 3030589706
• Artikelnr.: 59934027

Autorenporträt

Dr J. Robin Harris is a retired biochemist with specialism in macromolecular electron microscopy, now based in the UK.  He is the long-standing Series Editor of Subcellular Biochemistry. He is an Honorary Professor of the University of Mainz. Dr Jon Marles-Wright is a Senior Lecturer in the School of Natural and Environmental Sciences at Newcastle University. He has broad interest and experience in biomolecular X-ray  crystallography and cryoelectron microscopy.

Inhaltsangabe

Chapter 1. Structure, Dynamics and Function of the 26S Proteasome.- Chapter 2. Factor VIII and Factor V Membrane Bound Complexes.- Chapter 3. An Overview of DPS: Dual Acting Nanovehicles in Prokaryotes with DNA Binding and Ferroxidation Properties.- Chapter 4. Structure and Function of the Separase-Securin Complex.- Chapter 5. The DNA Replication Machine: Structure and Dynamic Function.- Chapter 6. Recent Progress in Structural Studies on the GT-C Superfamily of Protein Glycosyltransferases.- Chapter 7. How Structures of Complement Complexes Guide Therapeutic Design.- Chapter 8. Architecture and Assembly of the Bacterial Flagellar Motor Complex.- Chapter 9. Cellulosomes: Highly Efficient Cellulolytic Complexes.- Chapter 10. Leucine Dehydrogenase: Structure and Thermostability.- Chapter 11. Structure, Function and Physiology of 5-Hydroxytryptamine Receptors Subtype 3.- Chapter 12. The SF3b Complex Is an Integral Component of the Spliceosome and Targeted byNatural Product-based Inhibitors.- Chapter 13. Interaction Networks of Ribosomal Expansion Segments in Kinetoplastids.- Chapter 14. Hepatitis B Core Protein Capsids.- Chapter 15. Fibrinogen and Fibrin.- Chapter 16. Structural Organization and Protein-protein Interactions in Human Adenovirus Capsid.- Chapter 17. A Structural Perspective on Gene Repression by Polycomb Repressive Complex 2.- Chapter 18. Assembly and Function of the Anthrax Toxin Protein Translocation Complex.