This timely publication fills a large gap in the ophthalmic literature which has so far lacked a monograph on the clinically very important subject of macular edema. The book presents the most up-to-date scientific concepts concerning the etiology and pathogenesis of blood retinal barrier breakdown such as tight junction associated protein dysfunction, and changes in fluid transport properties of the retinal pigment epithelium. The bulk of the book is clinically oriented and addresses novel imaging and diagnostic techniques for the detection of macular edema as well as the clinical context of…mehr
This timely publication fills a large gap in the ophthalmic literature which has so far lacked a monograph on the clinically very important subject of macular edema. The book presents the most up-to-date scientific concepts concerning the etiology and pathogenesis of blood retinal barrier breakdown such as tight junction associated protein dysfunction, and changes in fluid transport properties of the retinal pigment epithelium. The bulk of the book is clinically oriented and addresses novel imaging and diagnostic techniques for the detection of macular edema as well as the clinical context of a panoply of ocular diseases which induce macular edema, such as diabetes, other vasculopathies, uveitis, and many others. New light is shed on the association between highly active antiretroviral therapy and the induction of macular edema in HIV-positive patients. Novel drug treatment regimens with steroids and carbonic anhydrase inhibitors as well as new ways of applying laser and surgical therapies are also discussed in detail, and practical treatment guidelines are given. This book will be helpful for vitreoretinal specialists as well as for the practising ophthalmologist confronted with patients suffering from macular edema.
The historical discovery of macular edema.- Basic science of macular edema.- Cellular mechanisms of blood-retinal barrier dysfunction in macular edema.- The molecular structure and function of the inner blood-retinal barrier.- Mechanisms of fluid accumulation in retinal edema.- Regulators of vascular permeability: potential sites for intervention in the treatment of macular edema.- Inhibition of membrane-bound carbonic anhydrase decreases subretinal pH and volume.- Clinical science of macular edema.- Macular hole formation in diabetic retinopathy: the role of coexisting macular edema.- Macular edema in retinal vein occlusion: Up-date from the central retinal vein occlusion study.- Visual prognosis of macular involvement in peripheral retinal vascular malformations.- The pathogenesis and clinical presentation of macular edema in inflammatory diseases.- Cystoid macular edema in a patient with acquired immunodeficiency syndrome and past ocular history of cytomegalovirus retinitis after initiation of protease inhibitors.- Is scierai fixation a safe procedure for intraocular lens implantation?.- Macular edema induced by phacoemulsification.- Cyst formation in optic disc pit maculopathy.- Optical coherence tomography (OCT) in macular edema.- Novel imaging techniques for diabetic macular edema.- Reproducibility of volumetric macular measurements in diabetic patients with the Heidelberg Retina Tomograph.- Diabetic maculopathy induced by vitreo-macular traction evaluation by optical coherence tomography (OCT).- Optical coherence tomography (OCT) in idiopathic polypoidal choroidal vasculopathy (IPCV).- New diagnostic tools for macular edema.- Treatment of cystoid macular edema with non-steroidal anti-inflammatory drugs and corticosteroids.- The role of carbonic anhydrase inhibitors in the management of macular edema.- Medical treatment of macular edema in patients with uveitis.- Treatment of uveitic macular edema with acetazolamide.- When and how to do a grid laser for diabetic macular edema.- Grid photocoagulation for focal diabetic macular edema with focal leaks and hard exsudates involving the peri-foveolar area.- Grid laser treatment of macular edema in macular branch retinal vein occlusion.- The place of vitreoretinal surgery in the treatment of macular oedema.- Vitrectomy for traction macular edema.- Vitrectomy for macular pucker and vitreomacular traction syndrome.- Cystotomy for diabetic cystoid macular edema.- Vitrectomy for macular edema combined with retinal vein occlusion.- Pars plana vitrectomy in diabetic macular edema.
The historical discovery of macular edema.- Basic science of macular edema.- Cellular mechanisms of blood-retinal barrier dysfunction in macular edema.- The molecular structure and function of the inner blood-retinal barrier.- Mechanisms of fluid accumulation in retinal edema.- Regulators of vascular permeability: potential sites for intervention in the treatment of macular edema.- Inhibition of membrane-bound carbonic anhydrase decreases subretinal pH and volume.- Clinical science of macular edema.- Macular hole formation in diabetic retinopathy: the role of coexisting macular edema.- Macular edema in retinal vein occlusion: Up-date from the central retinal vein occlusion study.- Visual prognosis of macular involvement in peripheral retinal vascular malformations.- The pathogenesis and clinical presentation of macular edema in inflammatory diseases.- Cystoid macular edema in a patient with acquired immunodeficiency syndrome and past ocular history of cytomegalovirus retinitis after initiation of protease inhibitors.- Is scierai fixation a safe procedure for intraocular lens implantation?.- Macular edema induced by phacoemulsification.- Cyst formation in optic disc pit maculopathy.- Optical coherence tomography (OCT) in macular edema.- Novel imaging techniques for diabetic macular edema.- Reproducibility of volumetric macular measurements in diabetic patients with the Heidelberg Retina Tomograph.- Diabetic maculopathy induced by vitreo-macular traction evaluation by optical coherence tomography (OCT).- Optical coherence tomography (OCT) in idiopathic polypoidal choroidal vasculopathy (IPCV).- New diagnostic tools for macular edema.- Treatment of cystoid macular edema with non-steroidal anti-inflammatory drugs and corticosteroids.- The role of carbonic anhydrase inhibitors in the management of macular edema.- Medical treatment of macular edema in patients with uveitis.- Treatment of uveitic macular edema with acetazolamide.- When and how to do a grid laser for diabetic macular edema.- Grid photocoagulation for focal diabetic macular edema with focal leaks and hard exsudates involving the peri-foveolar area.- Grid laser treatment of macular edema in macular branch retinal vein occlusion.- The place of vitreoretinal surgery in the treatment of macular oedema.- Vitrectomy for traction macular edema.- Vitrectomy for macular pucker and vitreomacular traction syndrome.- Cystotomy for diabetic cystoid macular edema.- Vitrectomy for macular edema combined with retinal vein occlusion.- Pars plana vitrectomy in diabetic macular edema.
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