This book deals with three key words- magnesium oxide, tissue conditioners and candida albicans. This book discusses about an in vitro study evaluating the efficacy of magnesium oxide powder incorporated into tissue conditioners against the growth of candida albicans . The key advantages of metallic oxides in tissue conditioners as a way of drug delivery is mentioned . This study can be of clinical significance, as incorporation of magnesium oxide sensitivity disc into tissue conditioners showed good inhibition of candida albicans and can be recommended for clinical use as well as for the incorporation of metallic oxide in tissue conditioners by manufacturers .