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Cortical developmental malformations (CDMs) refer to a broad spectrum of brain anomalies formed during embryogenesis. Their etiologies remain dominated by genetic and environmental causes. They are characterized by a great clinical polymorphism and an absence of clinical-radiological parallelism. MDCs are one of the main causes of drug-resistant epilepsy. Their typology is based on brain MRI which allows to distinguish neuronal and glial proliferation disorders, neuronal migration disorders and post-migratory cortical development disorders. Their management is multidisciplinary. Efforts remain…mehr

Produktbeschreibung
Cortical developmental malformations (CDMs) refer to a broad spectrum of brain anomalies formed during embryogenesis. Their etiologies remain dominated by genetic and environmental causes. They are characterized by a great clinical polymorphism and an absence of clinical-radiological parallelism. MDCs are one of the main causes of drug-resistant epilepsy. Their typology is based on brain MRI which allows to distinguish neuronal and glial proliferation disorders, neuronal migration disorders and post-migratory cortical development disorders. Their management is multidisciplinary. Efforts remain to be made in terms of antenatal diagnosis and surgical management, particularly in developing countries.
Autorenporträt
Dr. Barakizou HagerProfessor Associado, Universidade de Tunis El Manar, Faculdade de Medicina, Tunis.