Deirdre A. Devine / Robert E. W. Hancock (eds.)

Mammalian Host Defense Peptides

Herausgeber: Devine, Deirdre. A.

• Gebundenes Buch

Produktbeschreibung

This book draws together contributions from many leading scientists and reviews the most significant recent advances in the development of mammalian host defense peptides. These short, cationic single gene products have been isolated from a vast array of higher and lower organisms, and the conservation of function across so many species is an indication of their importance. Antimicrobial peptides are also the only new class of antimicrobial agent discovered in recent years, and there is interest in them as alternatives to conventional antibiotics.

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Produktdetails

• Verlag: Cambridge University Press
• Seitenzahl: 412
• Erscheinungstermin: 18. November 2004
• Englisch
• Abmessung: 235mm x 157mm x 27mm
• Gewicht: 745g
• ISBN-13: 9780521822206
• ISBN-10: 0521822203
• Artikelnr.: 22206240

Inhaltsangabe

1. Overview: antimicrobial peptides, as seen from a rear-view mirror R. I.
Lehrer; 2. Cationic antimicrobial peptides in regulation of commensal and
pathogenic microbial populations D. A. Devine; 3. Multiple functions of
antimicrobial peptides in host immunity D. Yang and J. J. Oppenheim; 4.
Therapeutic potential and applications of innate immunity peptides T. J.
Falla and L. Zhang; 5. Mammalian ß¿Defensins in mucosal defence G. Diamond,
D. Laube and M. Klein-Patel; 6. Biology and expression of the human
cathelicidin LL-37 G. Gudmundsson and B. Agerberth; 7. Antimicrobial
peptides of the alimentary tract of mammals C. Bevins and T. Ganz; 8.
Antimicrobial peptides suppress microbial infections and sepsis in animal
models K. A. Brogden, M. Ackermann, J. Zabner and M. J. Welsh; 9. Bacterial
structure and physiology: influence on susceptibility to antimicrobial
peptides R. E. W. Hancock; 9. The antifungal mechanisms of antimicrobial
peptides E. J. Helmerhorst and F. G. Oppenheim; 10. Antimicrobial peptides
from platelets in defence against cardiovascular infections M. R. Yeaman;
11. Mechanisms of bacterial resistance to antimicrobial peptides R. Tamayo,
A. C. Portillo and J. S. Gunn; 12. Roles of antimicrobial peptides in
pulmonary disease R. Bals.