Malformation disease of mango (Mangifera indica) initially noted in patches in India has now turned into a global menace wherever mango is grown. The challenge posed by the problem attracted interest of Scientists from various disciplines, continue to do so, and will attract their attention until the problem is understood threadbare, and resolved. For a long time, due to complex nature of the disease, the cause and causal agent was both hotly debated. Only in recent years, the issue of the etiology of the disease has been resolved, epidemiology has been worked out to a large extent and silver bullet control measures have been replaced by IPM strategy based on the information generated on the physiology of pathogenesis and epidemiology of the disease.