Marine Neurotoxins, Volume Five provides comprehensive information on marine toxins present in the human food chain and the affecting targets relevant for the functioning of the brain and our nervous system, covering all the information available on their action on the physiology of neurons and glial cells, both "in vivo" or "in vitro." New sections in this release include Guanidinium Toxins: Evolution, Mode of Action and Chemical Ecology, Amnesic: Domoic Acid, Neurotoxic: Ciguatoxin and Brevetoxin, Neurotoxic: Cyclic Imines, Potentially Neurotoxic: Okadaic acid and analogues, Potentially…mehr
Marine Neurotoxins, Volume Five provides comprehensive information on marine toxins present in the human food chain and the affecting targets relevant for the functioning of the brain and our nervous system, covering all the information available on their action on the physiology of neurons and glial cells, both "in vivo" or "in vitro." New sections in this release include Guanidinium Toxins: Evolution, Mode of Action and Chemical Ecology, Amnesic: Domoic Acid, Neurotoxic: Ciguatoxin and Brevetoxin, Neurotoxic: Cyclic Imines, Potentially Neurotoxic: Okadaic acid and analogues, Potentially Neurotoxic: Palytoxin, and Methods for assessing the presence of marine neurotoxins.
Antonello Novelli was born in Milan (Italy) and obtained his Degree (Laurea) in Biology in 1978 from the University of Studies of Milan, followed by the Ph.D. in Experimental Pharmacology in 1982, from the same institution. He has been working at the Neurological Institute "C. Besta? in Milan (1980), at the NIMH, St. Elizabeth's Hospital in Washington D.C. and at the NINDS in Bethesda for more than 6 years (1983-89), and for shorter periods in the laboratory of Biophysics at the International School for Advanced Studies (SISSA) in Trieste, Italy, as Visiting Scientist. At present, he is Permanent Professor of Psychobiology and Vice-Dean of the Faculty of Psychology at the University of Oviedo, Spain, and he is developing his research activity within the University Institute of Biotechnology of Asturias (IUBA), in the Department of Biochemistry and Molecular Biology, Laboratory of Brain Science and Technology, in collaboration with Dr. MT Fernández-Sánchez. Dr. Novelli is also a me
mber of the Sanitary Institute of the Princedom of Asturias (ISPA). His research interests are focused on the mechanisms and biomarkers of neurotoxicity, neurodegeneration and neuroprotection in cultured neurons following exposure to a variety of conditions and stimuli, by using multiple techniques, including the emerging extracellular electrophysiology by microelectrode arrays. Seafood toxins have been one of his constant topic of research since the Canadian episode of human intoxication by domoic acid in 1987, and the presentation of his work at the first meeting on domoic acid toxicity in 1989 in Ottawa.
Inhaltsangabe
1. Marine guanidinium neurotoxins: Biogenic origins and interactions, biosynthesis and pharmacology Allan D. Cembella and Lorena M. Durán-Riveroll 2. Domoic acid R. Andrew Tasker 3. Neurotoxic: Ciguatoxin and brevetoxin-From excitotoxicity to neurotherapeutics Thomas F. Murray 4. Marine-derived nicotinic receptor antagonist toxins: Pinnatoxins and alpha conotoxins Shane Dennis Hellyer 5. Potential neurotoxins: Okadaic acid and analogs Antonello Novelli, Antonio Hernández Daranas, David Cabrera García, Fernando Ascencio Salazar and Maria Teresa Fernández-Sánchez 6. Potential neurotoxins: Palytoxins Maria-Teresa Fernández-Sánchez, David Cabrera-García, Anabel Pérez-Gómez and Antonello Novelli 7. The wide spectrum of methods available to study marine neurotoxins Mònica Campàs, Mounira Alkassar, Greta Gaiani, Sandra Leonardo, Maria Rambla-Alegre and Jorge Diogène
1. Marine guanidinium neurotoxins: Biogenic origins and interactions, biosynthesis and pharmacology Allan D. Cembella and Lorena M. Durán-Riveroll 2. Domoic acid R. Andrew Tasker 3. Neurotoxic: Ciguatoxin and brevetoxin-From excitotoxicity to neurotherapeutics Thomas F. Murray 4. Marine-derived nicotinic receptor antagonist toxins: Pinnatoxins and alpha conotoxins Shane Dennis Hellyer 5. Potential neurotoxins: Okadaic acid and analogs Antonello Novelli, Antonio Hernández Daranas, David Cabrera García, Fernando Ascencio Salazar and Maria Teresa Fernández-Sánchez 6. Potential neurotoxins: Palytoxins Maria-Teresa Fernández-Sánchez, David Cabrera-García, Anabel Pérez-Gómez and Antonello Novelli 7. The wide spectrum of methods available to study marine neurotoxins Mònica Campàs, Mounira Alkassar, Greta Gaiani, Sandra Leonardo, Maria Rambla-Alegre and Jorge Diogène
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