Matrix Metalloproetinases in Head and Neck Squamous Cell Carcinoma - Shrestha, Bijayata;subedi, Sushil
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Degradation of extracellular matrix is an important feature involved in physiological process such as normal development, morphogenesis, tissue repair and remodelling and pathological process such as tumor invasion and metastasis. Matrixmetalloproteinases (MMP) are Zn++ dependent enzymes that can cause degradation of extracellular matrix proteins. MMPs are overexpressed in squamous cell carcinoma and are of prognostic significance.

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Produktbeschreibung
Degradation of extracellular matrix is an important feature involved in physiological process such as normal development, morphogenesis, tissue repair and remodelling and pathological process such as tumor invasion and metastasis. Matrixmetalloproteinases (MMP) are Zn++ dependent enzymes that can cause degradation of extracellular matrix proteins. MMPs are overexpressed in squamous cell carcinoma and are of prognostic significance.
Autorenporträt
Renouned Oral Pathologist from Nepal working as Assistant Professor in Chitwan Medical College, Bharatpur,Nepal and has completed MDS from Kathmandu University, Nepal in 2011 and has contributed articles in national and international journals, contributed book chapters and has keen interest in head and Neck Cancer.