Masahiro Kinoshita

Mechanism of Functional Expression of the Molecular Machines

• Broschiertes Buch

Produktbeschreibung

This brief discusses the mechanism of functional expression of a protein or protein complex utilizing the ATP hydrolysis cycle or proton-motive force from a unique point of view focused on the roles of water. A variety of processes are considered such as the unidirectional movement of a linear-motor protein along a filament, insertion of an unfolded protein into a chaperonin and release of the folded protein from it, transport of diverse substrates across the membrane by a transporter, and directed rotation of the central subunit within a rotatory motor protein complex. These topics are discussed in a unified manner within the same theoretical framework. The author argues that water plays imperative roles in the functional expression of these molecular machines. A pivotal factor is the entropic force or potential originating from the translational displacement of water molecules coexisting with the molecular machines in the entire system.

Produktdetails

• SpringerBriefs in Molecular Science
• Verlag: Springer / Springer Nature Singapore / Springer, Berlin
• Artikelnr. des Verlages: 978-981-10-1484-0
• 1st ed. 2016
• Seitenzahl: 80
• Erscheinungstermin: 22. Juni 2016
• Englisch
• Abmessung: 235mm x 155mm x 5mm
• Gewicht: 137g
• ISBN-13: 9789811014840
• ISBN-10: 9811014841
• Artikelnr.: 44898355

Autorenporträt

Prof. Dr. Masahiro KinoshitaInstitute of Advanced Energy Kyoto University

Inhaltsangabe

Introduction.- Importance of Translational, Configurational Entropy of Water.- Molecular Machines.- Concluding Remarks: Mechanism of Functional Expression Common in the Molecular Machines.