Mechanisms and Consequences of Proton Transport

Mechanisms and Consequences of Proton Transport

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"The principal focus of Mechanisms and Consequences of Proton Transport is on the gastric parietal cell and the acid secretory apparatus: how it operates and the consequences of malfunction. Key topics include: - the fundamental structure and molecular operation of the gastric H+/K+ exchange pump; - gene targeting studies directed at functional changes in the gastric epithelium and its ability to deal with the pathological consequences of acid and Helicobacter pylori infection; and - regulation of parietal cell activation by protein kinases and ion transport pathways; the parietal cell as a mo...