Mechanisms and Therapy of Liver Cancer, Volume 149, presents the latest information on the incidence and mortality of liver cancer research and how it has gained significant momentum because of its direct causative association with obesity-induced fatty liver disease. The literature on liver cancer is moving fast with exciting, novel findings, providing new insights reflected in the following updated chapters: Introduction and molecular classification of HCC, Signaling Pathways in Liver Cancer, HCV and HCC, NASH and HCC, Microbiome and Metabolic Abnormalities in HCC, Systemic Therapy of Liver…mehr
Mechanisms and Therapy of Liver Cancer, Volume 149, presents the latest information on the incidence and mortality of liver cancer research and how it has gained significant momentum because of its direct causative association with obesity-induced fatty liver disease. The literature on liver cancer is moving fast with exciting, novel findings, providing new insights reflected in the following updated chapters: Introduction and molecular classification of HCC, Signaling Pathways in Liver Cancer, HCV and HCC, NASH and HCC, Microbiome and Metabolic Abnormalities in HCC, Systemic Therapy of Liver Cancer, Immunotherapy of Liver Cancer, and Desmoplastic Tumor Microenvironment and Intrahepatic Cholangiocarcinoma Progression: Mechanisms and Therapeutic Implications.
Dr. Sarkar received his MBBS from Dhaka Medical College, Bangladesh and PhD from Nagoya University, Japan. After postdoctoral training in Columbia University, NY he joined Virginia Commonwealth University (VCU) as a faculty where he is now a Professor in the Department of Human and Molecular Genetics, and Associate Director of Education and Training at Massey Cancer Center. Dr. Sarkar's research focuses on identifying novel regulators of hepatocellular carcinoma (HCC), especially obesity-induced HCC, and developing targeted gene- and immunotherapy based on the accrued knowledge. Dr. Sarkar has published more than 280 papers and his research is funded by NCI, NIDDK and DOD.
Inhaltsangabe
1. Hepatocellular carcinoma (HCC): Epidemiology, etiology and molecular classification Saranya Chidambaranathan-Reghupaty, Paul B. Fisher, and Devanand Sarkar 2. Signaling pathways in hepatocellular carcinoma Teresa Garcia-Lezana, Juan Luis Lopez-Canovas, and Augusto Villanueva 3. Hepatitis C virus associated hepatocellular carcinoma Mousumi Khatun, Ranjit Ray, and Ratna B. Ray 4. NAFLD-related HCC Bubu A. Banini and Arun J. Sanyal 5. Atypical immunometabolism and metabolic reprogramming in liver cancer: Deciphering the role of gut microbiome Rachel M. Golonka and Matam Vijay-Kumar 6. Systemic therapy of liver cancer Tarik Demir, Sunyoung S. Lee, and Ahmed O. Kaseb 7. Immunotherapy in hepatocellular cancer Christos Fountzilas, Rachel Evans, Sabah Alaklabi, and Renuka Iyer 8. Intrahepatic cholangiocarcinoma: Morpho-molecular pathology, tumor reactive microenvironment, and malignant progression Alphonse E. Sirica, Mario Strazzabosco, and Massimiliano Cadamuro
1. Hepatocellular carcinoma (HCC): Epidemiology, etiology and molecular classification Saranya Chidambaranathan-Reghupaty, Paul B. Fisher, and Devanand Sarkar 2. Signaling pathways in hepatocellular carcinoma Teresa Garcia-Lezana, Juan Luis Lopez-Canovas, and Augusto Villanueva 3. Hepatitis C virus associated hepatocellular carcinoma Mousumi Khatun, Ranjit Ray, and Ratna B. Ray 4. NAFLD-related HCC Bubu A. Banini and Arun J. Sanyal 5. Atypical immunometabolism and metabolic reprogramming in liver cancer: Deciphering the role of gut microbiome Rachel M. Golonka and Matam Vijay-Kumar 6. Systemic therapy of liver cancer Tarik Demir, Sunyoung S. Lee, and Ahmed O. Kaseb 7. Immunotherapy in hepatocellular cancer Christos Fountzilas, Rachel Evans, Sabah Alaklabi, and Renuka Iyer 8. Intrahepatic cholangiocarcinoma: Morpho-molecular pathology, tumor reactive microenvironment, and malignant progression Alphonse E. Sirica, Mario Strazzabosco, and Massimiliano Cadamuro
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"Provides the latest information on liver cancer research; Offers outstanding and original reviews on a range of topics focused on liver cancer; Serves as an indispensable reference on liver cancer for researchers and students alike." --Anticancer Research
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