Albert J Courey

Mechanisms in Transcriptional Regulation

• Broschiertes Buch

Produktbeschreibung

Mechanisms in Transcriptional Regulation provides a concise discussion of the fundamental concepts in transcription and its regulation. Beginning with an overview of RNA polymerases and the general transcriptional machinery, this book goes on to cover the mechanisms of transcriptional activation, the histone code hypothesis, the epigenetic control of transcription, and combinatorial control in signaling and development. Mechanisms in Transcriptional Regulation contains many features designed to aid understanding. More than 80 figures crystallize and amplify the ideas presented in the text. Boxes set off from the main text offer background information on important theoretical concepts and experimental methods. Thought-provoking problems test students' understanding of key concepts. Extensive reading lists included in each chapter provide guidance for further studies. In addition, the book is accompanied by a website that includes all the art from the book in downloadable format - www.blackwellpublishing.com/courey. These features make this text an ideal resource for upper-level undergraduate, graduate, and postgraduate students alike.

Produktdetails

• Verlag: Wiley
• Seitenzahl: 248
• Erscheinungstermin: 21. April 2008
• Englisch
• Abmessung: 244mm x 172mm x 19mm
• Gewicht: 586g
• ISBN-13: 9781405103701
• ISBN-10: 1405103701
• Artikelnr.: 22949990

Autorenporträt

Albert J. Courey has taught undergraduate and graduate students about mechanisms of transcription and its regulation for the last 16 years as Professor of Biochemistry at UCLA. He also directs an active research program examining the mechanisms of transcriptional regulation during fruit fly development.

Inhaltsangabe

Preface.

1. The Vocabulary of Transcription.

2. RNA Polymerases and the Transcription Cycle.

3. The Eukaryotic Basal Machinery.

4. Mechanisms of Transcriptional Activation.

5. Transcriptional control through the modification of chromatinstructure.

6. The Epigenetic Control of Transcription.

7. Combinatorial Control in Development and SignalTransduction.

Answers to problems.

Glossary.

Index