Mechanisms Linking Aging, Diseases and Biological Age Estimation

Herausgeber: Zapico, Sara C.

• Gebundenes Buch

Produktbeschreibung

This book focuses on four of the hallmarks of aging: aspartic acid racemization, advanced glycation end products, telomere shortening and mitochondrial mutations; describing their role in aging and diseases; and their application to age-at-death estimation in forensic sciences in greater depth, displaying the interconnecting pathways among these processes. An additional chapter related to Epigenetics and its role in aging, diseases, and forensic age estimation is also included. This book is aimed at a broad audience: from students being introduced to aging, diseases, and forensic science research to scientists in biomedicine and forensics complementing their knowledge in their respective fields while also increasing their knowledge in other disciplines.

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Produktdetails

• Verlag: Taylor & Francis Inc
• Seitenzahl: 275
• Erscheinungstermin: 21. Dezember 2016
• Englisch
• Abmessung: 200mm x 140mm x 20mm
• Gewicht: 332g
• ISBN-13: 9781498709699
• ISBN-10: 1498709699
• Artikelnr.: 54589778

Autorenporträt

Sara C. Zapico

Inhaltsangabe

Aspartic Acid Racemization. Introduction to Aspartic Acid Racemization.
Aspartic Acid Racemization on Aging. Aspartic Acid Racemization and Aging
in Cartilaginous Tissue. Racemization and isomerization of Aspartyl
Residues in Amyloid Peptides Involved in the Development of Alzheimer¿s
Disease. Aspartic Acid Racemization: Applications to Forensic and
Archaeological Age Estimation. Advanced Glycation Endproducts. Advanced
Glycation Endproducts: An Introduction. Advanced Glycation and Aging.
AGE-RAGE Axis in the Aging and Diabetic Heart: Prime Target for Adjunctive
Therapeutic Intervention. Advanced Glycation Endproducts in Aging Skin.
Advanced Glycation Endproducts and Neurological Diseases. Advanced
Glycation Endproducts for Age at Death Estimation. Telomeres. Introduction
to Telomere Biology. Role of Telomeres in Aging. Telomeres and
Cardiovascular Disease: Facts, Controversies and Limitations. Telomeres in
Cancer. Forensic Application of Telomere Shortening in Age-at-death
Estimation. Mitochondrial DNA Mutations. Introduction to Mitochondria
Biology. Mitochondrial DNA Mutations and Aging. Mitochondrial DNA Mutations
and Mitochondrial Diseases. Reproductive Approaches to Prevent the
Transmission of Mitochondrial Diseases. Mitochondrial DNA Mutations and
Neurodegenerative Diseases. An Overview of mtDNA Analysis for Age-at-death
Estimation in Forensic Sciences. Epigenetics. Epigenetics: Its Role in
Aging, Diseases and Biological Age Estimation.