Mechanobiology of the Endothelium

Herausgeber: Aranda-Espinoza, Helim

• Gebundenes Buch

Produktbeschreibung

The endothelium is an excellent example of where biology meets physics and engineering. It must convert mechanical forces into chemical signals to maintain homeostasis. It also controls the immune response, drug delivery through the vasculature, and cancer metastasis. Basic understanding of these processes is starting to emerge and the knowledge gained from research is now being used in applications from drug delivery to imaging modalities. This book reviews current knowledge in mechanobiology of the endothelium and its implications for the development of theranostic devices.

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Produktdetails

• Verlag: CRC Press
• Seitenzahl: 280
• Erscheinungstermin: 12. Februar 2015
• Englisch
• Abmessung: 231mm x 155mm x 20mm
• Gewicht: 522g
• ISBN-13: 9781482207248
• ISBN-10: 1482207249
• Artikelnr.: 40033711

Autorenporträt

Helim Aranda-Espinoza

Inhaltsangabe

The Endothelium as a Mechanosensor. Mechanobiology of the Endothelial
Nucleus. Cancer Metastasis and Biomechanics of the Endothelium. Valvular
Endothelial Mechanobiology. Environmental Factors that Influence the
Response of the Endothelium to Flow. Differential Response of the
Endothelium to Simultaneous Chemical and Mechanical Stimulation in
Inflammation Response. The Role of Cholesterol and Lipoproteins in Control
of Endothelial Biomechanics. Implications of Fluid Shear Stress in
Capillary Sprouting during Adult Microvascular Network Remodeling.
Endothelial Cell Adhesion Molecules and Drug Delivery Applications.
Leukocyte Transendothelial Migration: A Biophysical Event. The Immune
System as a Theranostic Device.