Andre Kamkin / Irina Kiseleva (eds.)

Mechanosensitive Ion Channels

Herausgegeben:Kamkin, Andre; Kiseleva, Irina;Mitarbeit:Lozinsky, I.; Lab, M.J.; Hescheler, J.

• Gebundenes Buch

Produktbeschreibung

This book explores the latest data dealing with mechanosensitive channels research results. It was compiled by a group of internationally recognized scientists leading in the field of mechanosensitive ion channels or mechanically gated channels and signaling cascades research. Key problems of cell mechanobiology are also discussed. As a whole, the volume dwells on the major issues of mechanical stress influencing the ion channels and intracellular signaling pathways.

Produktdetails

• Mechanosensitivity in Cells and Tissues 1
• Verlag: Springer / Springer Netherlands / Springer, Berlin
• Artikelnr. des Verlages: 11783886, 978-1-4020-6425-8
• 2008 edition
• Seitenzahl: 382
• Erscheinungstermin: 14. November 2007
• Englisch
• Abmessung: 242mm x 164mm x 22mm
• Gewicht: 713g
• ISBN-13: 9781402064258
• ISBN-10: 140206425X
• Artikelnr.: 22960249

Inhaltsangabe

Foreword I.- Foreword II.- Editorial Mechanically gated channels and mechanosensitive channels.- Part I. Mechanosensitive Channels.- Experimental methods of studying of mechanosensitive channels and possible errors in data interpretation.- The role of lipid bilayer mechanics in mechanosensation.- Mechanosensitive channels gated by membrane tension: bacteria and beyond.- Computational approaches in studies of bacterial mechanosensitive channels.- Mechanosensory transduction in the nematode Caenorhabditis elegans.- Mechanosensitive ion channels in odontoblasts.- Potassium ion channels in articular chondrocytes: putative roles in mechanotransduction, metabolic regulation and cell proliferation.- Osmotransduction through volume-sensitive Cl - channels.- Mechanosensitive channel TRPV4. A micro-machine converting physical force into an ion flow. Part II Mechanosensitive Signaling Cascades.- Mechanosensitive purinergic calcium signalling in articular chondrocytes.- Signal transduction pathways involved in mechanotransduction in osteoblastic and mesenchymal stem cells.- Caveolae: Co-ordinating centres for mechanotransduction in the heart?- Multimodal activation and regulation of neuronal mechanosensitive cation channels.- Rregulation of intracellular signal transduction pathways by mechanosensitive ion channels. Part III. Cell Mechanobiology.- The effects of mechanical stimulation on vertebrate hearts: a question of class.- Mechanobiology of fibroblasts