This highly illustrated, diagnostic guidebook provides a single comprehensive source of essential information to enable non-specialists to diagnose lymph node and related diseases with confidence. The text is didactic and practical, covering reactive as well as malignant conditions. Diagnosis of Lymphoproliferative Diseases approaches the disorders based on the WHO classification and is edited by members of the WHO panel for the classification of lymphomas. This second edition contains over 1000 high quality, digitised colour images and tables of essential criteria for each diagnosis. New…mehr
This highly illustrated, diagnostic guidebook provides a single comprehensive source of essential information to enable non-specialists to diagnose lymph node and related diseases with confidence. The text is didactic and practical, covering reactive as well as malignant conditions. Diagnosis of Lymphoproliferative Diseases approaches the disorders based on the WHO classification and is edited by members of the WHO panel for the classification of lymphomas. This second edition contains over 1000 high quality, digitised colour images and tables of essential criteria for each diagnosis. New features include: Full discussion of immunostaining, the core of modern diagnosis Variant forms and technical issues This authoritative guide is an essential reference for haematologists, haematopathologists, general pathologists, diagnostic histopathologists and oncologists.
Pierre-Alain Clavien, MD, PhD, FACS, FRCS (Eng), FRCS (Ed), Professor and Chairman, Department of Surgery. Head, Division of Visceral & Transplantation Surgery, University Hospital Zurich, Switzerland Professor Clavien is a world-wide renowned surgeon-scientist, currently professor and chairman of the Department of Surgery in Zurich, Switzerland. His areas of research include organ preservation, liver ischemia-reperfusion injury and regeneration, and pathogenesis of cancer, as well as outcome research. He received many competitive grants and awards, including one of the most prestigious prices for scientific research, the Otto Naegeli Award. Dr James Trotter is the Medical Director of Liver Transplantation at Baylor University Medical Center at Dallas. Dr. Trotter's primary interests include end-stage liver disease and the management of liver transplant candidates and recipients. Dr. Trotter specializes in hepatitis C, ascites, complications of portal hypertension, including esophageal varices and hepatic encephalopathy. He also has vast experience in the management of medical complications after liver transplantation including immunosuppression in liver transplant recipients and the treatment of hepatitis C before and after liver transplantation.
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Contributors ix Preface xv Part 1 Management of the potential transplant recipient 1 Selection and evaluation of the recipient (including retransplantation) 3 Audrey Coilly and Didier Samuel 2 Monitoring the patient awaiting liver transplantation 13 Andreas Geier and Beat Müllhaupt 3 Management of portal hypertension 26 Juan Carlos Garcia-Pagan Juan G. Abraldes and Jaime Bosch 4 Management of renal disease in the liver transplant candidate 39 Andrés Cárdenas and Pere Ginès 5 Management of hepatopulmonary syndrome and portopulmonary hypertension 51 Victor I. Machicao and Michael B. Fallon 6 Psychiatric and substance abuse evaluation of the potential liver transplant recipient 62 Thomas P. Beresford 7 Organ allocation in liver transplantation: ethics organ supply and evidencebased practice 75 Nicole Siparsky David Axelrod and Richard B. Freeman 8 Viral hepatitis and transplantation 88 Geoffrey W. McCaughan 9 Metabolic liver diseases 97 Maureen M.J. Guichelaar and Michael R. Charlton 10 Cholestatic and autoimmune liver disease 110 Ulrich Beuers 11 Hepatocellular carcinoma 121 Maria Reig Alejandro Forner and Jordi Bruix 12 Cholangiocarcinoma 133 Howard C. Masuoka Gregory J. Gores and Charles B. Rosen 13 Rare indications for liver transplantation 145 Stevan A. Gonzalez 14 Liver transplantation in HIV patients 155 Marion G. Peters and Peter G. Stock 15 Living-donor liver transplantation 162 Robert S. Brown Jr 16 Fulminant hepatic failure 176 Michael A. Heneghan and William Bernal Part 2 Donor issues and management in the perioperative period 17 Extended-criteria donor 191 Ashraf Mohammad El-Badry and Mickael Lesurtel 18 Liver transplantation using donors after cardiac death 201 Paolo Muiesan Laura Tariciotti and Chiara Rocha 19 Transmission of malignancies and infection through donor organs 216 Aaron M. Winnick and Lewis Teperman 20 The transplant operation 229 Philipp Dutkowski Olivier de Rougemont and Pierre-Alain Clavien 21 Difficult surgical patients 238 Philipp Dutkowski Stefan Breitenstein and Pierre-Alain Clavien 22 Domino and split-liver transplantation 246 Abhideep Chaudhary and Abhinav Humar 23 Surgical aspects of living-donor transplantation 255 Kelvin K.C. Ng and Sheung Tat Fan 24 Anesthesia 266 Beatrice Beck-Schimmer 25 Coagulation and blood transfusion management 276 Herman G.D. Hendriks Ton Lisman and Robert J. Porte 26 Critical care of the liver transplant recipient 286 Markus Béchir Erik Schadde and Philipp Dutkowski 27 Rejection and immunosuppression trends in liver transplantation 297 James F. Trotter 28 Vascular complications after liver transplantation 311 Goran Klintmalm and Srinath Chinnakotla 29 Biliary complications following liver transplantation 319 Sanna op den Dries Robert C. Verdonk and Robert J. Porte 30 Role of histopathology 332 Achim Weber Part 3 Chronic problems in the transplant recipient 31 Medical problems after liver transplantation 347 Eberhard L. Renner and Marco Puglia 32 Prevention and treatment of recurrent HBV and HCV infection 361 Ed Gane 33 Recurrence of the original disease 372 James Neuberger 34 Infections in the liver transplant recipient 380 Nicolas J. Mueller and Jay A. Fishman 35 Cutaneous diseases in liver transplant recipients 389 Sylvie Euvrard and Jean Kanitakis 36 Post-transplant lymphoproliferative disorder and other malignancies after liver transplantation 398 Natasha Chandok and Kymberly D.S. Watt 37 Sexual function and fertility after liver transplantation 406 Andreas Geier and Beat Müllhaupt Part 4 Pediatric liver transplantation 38 Special considerations in pediatric liver transplantation 419 Brandy Ries Lu and Ronald J. Sokol Multiple choice questions 431 Answers 446 Index 451
Contributors ix Preface xv Part 1 Management of the potential transplant recipient 1 Selection and evaluation of the recipient (including retransplantation) 3 Audrey Coilly and Didier Samuel 2 Monitoring the patient awaiting liver transplantation 13 Andreas Geier and Beat Müllhaupt 3 Management of portal hypertension 26 Juan Carlos Garcia-Pagan Juan G. Abraldes and Jaime Bosch 4 Management of renal disease in the liver transplant candidate 39 Andrés Cárdenas and Pere Ginès 5 Management of hepatopulmonary syndrome and portopulmonary hypertension 51 Victor I. Machicao and Michael B. Fallon 6 Psychiatric and substance abuse evaluation of the potential liver transplant recipient 62 Thomas P. Beresford 7 Organ allocation in liver transplantation: ethics organ supply and evidencebased practice 75 Nicole Siparsky David Axelrod and Richard B. Freeman 8 Viral hepatitis and transplantation 88 Geoffrey W. McCaughan 9 Metabolic liver diseases 97 Maureen M.J. Guichelaar and Michael R. Charlton 10 Cholestatic and autoimmune liver disease 110 Ulrich Beuers 11 Hepatocellular carcinoma 121 Maria Reig Alejandro Forner and Jordi Bruix 12 Cholangiocarcinoma 133 Howard C. Masuoka Gregory J. Gores and Charles B. Rosen 13 Rare indications for liver transplantation 145 Stevan A. Gonzalez 14 Liver transplantation in HIV patients 155 Marion G. Peters and Peter G. Stock 15 Living-donor liver transplantation 162 Robert S. Brown Jr 16 Fulminant hepatic failure 176 Michael A. Heneghan and William Bernal Part 2 Donor issues and management in the perioperative period 17 Extended-criteria donor 191 Ashraf Mohammad El-Badry and Mickael Lesurtel 18 Liver transplantation using donors after cardiac death 201 Paolo Muiesan Laura Tariciotti and Chiara Rocha 19 Transmission of malignancies and infection through donor organs 216 Aaron M. Winnick and Lewis Teperman 20 The transplant operation 229 Philipp Dutkowski Olivier de Rougemont and Pierre-Alain Clavien 21 Difficult surgical patients 238 Philipp Dutkowski Stefan Breitenstein and Pierre-Alain Clavien 22 Domino and split-liver transplantation 246 Abhideep Chaudhary and Abhinav Humar 23 Surgical aspects of living-donor transplantation 255 Kelvin K.C. Ng and Sheung Tat Fan 24 Anesthesia 266 Beatrice Beck-Schimmer 25 Coagulation and blood transfusion management 276 Herman G.D. Hendriks Ton Lisman and Robert J. Porte 26 Critical care of the liver transplant recipient 286 Markus Béchir Erik Schadde and Philipp Dutkowski 27 Rejection and immunosuppression trends in liver transplantation 297 James F. Trotter 28 Vascular complications after liver transplantation 311 Goran Klintmalm and Srinath Chinnakotla 29 Biliary complications following liver transplantation 319 Sanna op den Dries Robert C. Verdonk and Robert J. Porte 30 Role of histopathology 332 Achim Weber Part 3 Chronic problems in the transplant recipient 31 Medical problems after liver transplantation 347 Eberhard L. Renner and Marco Puglia 32 Prevention and treatment of recurrent HBV and HCV infection 361 Ed Gane 33 Recurrence of the original disease 372 James Neuberger 34 Infections in the liver transplant recipient 380 Nicolas J. Mueller and Jay A. Fishman 35 Cutaneous diseases in liver transplant recipients 389 Sylvie Euvrard and Jean Kanitakis 36 Post-transplant lymphoproliferative disorder and other malignancies after liver transplantation 398 Natasha Chandok and Kymberly D.S. Watt 37 Sexual function and fertility after liver transplantation 406 Andreas Geier and Beat Müllhaupt Part 4 Pediatric liver transplantation 38 Special considerations in pediatric liver transplantation 419 Brandy Ries Lu and Ronald J. Sokol Multiple choice questions 431 Answers 446 Index 451
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