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This book deals with the following medical aspects concerning human vagina: sexual differentiation and embryonic development, anatomy, histology and morphological changes, effect of hormones on vaginal mucosa and vaginal flora, normal flora, infectious and non-infectious vaginitis, innate and adaptive immunity, oxidative stress, vaginal atrophy, and benign and malignant tumors of vagina. This book can be used as a guide to gynecologists and undergraduate and postgraduate students who have interests in this medical field as it comprises satisfactorily many medical and clinical illustrations and talks about this portion of female reproductive system. Moreover, even common women can get benefit from this book as they can return to it and learn what complications concerning this portion of female genitalia they might face.