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Medicinal Fluorine
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The diverse applications of fluorine in bioorganic and medicinal chemistryThe discovery of fluorouracil, fluorocorticoids, and fluoroquinolones has led to expanded interest in and usage of fluorine in chemistry. The first comprehensive reference dedicated to detailing the influence of fluorine on the structural properties of a molecule and on a molecule's biological behavior, Bioorganic and Medicinal Chemistry of Fluorine uses examples of fluorinated drugs to provide a thorough overview of the role of fluorine in pharmaceutical science and development. Covering established drugs as well as inn...
The diverse applications of fluorine in bioorganic and medicinal chemistry
The discovery of fluorouracil, fluorocorticoids, and fluoroquinolones has led to expanded interest in and usage of fluorine in chemistry. The first comprehensive reference dedicated to detailing the influence of fluorine on the structural properties of a molecule and on a molecule's biological behavior, Bioorganic and Medicinal Chemistry of Fluorine uses examples of fluorinated drugs to provide a thorough overview of the role of fluorine in pharmaceutical science and development. Covering established drugs as well as innovative and promising ideas, it includes:
An introduction to the structural, physical, and chemical properties of fluorinated compounds and their preparations
An examination of fluorinated analogues of natural products, fluorinated amino acids and peptides, and saccharidic derivatives
A discussion of the inhibition of enzymes by fluorinated compounds
An overview of existing fluorinated pharmaceuticals as well as some in development, categorized according to their therapeutic classes
Complete with references for further study, this is the premier resource on fluorine for pharmaceutical and medicinal chemists in academia and industry, researchers in organic chemistry and biochemistry, and advanced students and educators in pharmaceutical and medicinal chemistry, biochemistry, and organic chemistry.
The discovery of fluorouracil, fluorocorticoids, and fluoroquinolones has led to expanded interest in and usage of fluorine in chemistry. The first comprehensive reference dedicated to detailing the influence of fluorine on the structural properties of a molecule and on a molecule's biological behavior, Bioorganic and Medicinal Chemistry of Fluorine uses examples of fluorinated drugs to provide a thorough overview of the role of fluorine in pharmaceutical science and development. Covering established drugs as well as innovative and promising ideas, it includes:
An introduction to the structural, physical, and chemical properties of fluorinated compounds and their preparations
An examination of fluorinated analogues of natural products, fluorinated amino acids and peptides, and saccharidic derivatives
A discussion of the inhibition of enzymes by fluorinated compounds
An overview of existing fluorinated pharmaceuticals as well as some in development, categorized according to their therapeutic classes
Complete with references for further study, this is the premier resource on fluorine for pharmaceutical and medicinal chemists in academia and industry, researchers in organic chemistry and biochemistry, and advanced students and educators in pharmaceutical and medicinal chemistry, biochemistry, and organic chemistry.
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