"Medicinal Foods as Potential Therapies for Type-2 Diabetes: The Chemical and Pharmacological Basis of their Action is the first book to focus on active pharmacological principles that modulate diabetes, associated risk factors, and complications and the mechanism of action of widely used anti-diabetic herbal plants, rather than the nutritional composition of the foods. It provides up-to-date information on the scientific basis of some acclaimed antidiabetic super fruits, species and other food ingredients. The global incidence of diabetes and its major risk factor, obesity, is growing with…mehr
"Medicinal Foods as Potential Therapies for Type-2 Diabetes: The Chemical and Pharmacological Basis of their Action is the first book to focus on active pharmacological principles that modulate diabetes, associated risk factors, and complications and the mechanism of action of widely used anti-diabetic herbal plants, rather than the nutritional composition of the foods. It provides up-to-date information on the scientific basis of some acclaimed antidiabetic super fruits, species and other food ingredients. The global incidence of diabetes and its major risk factor, obesity, is growing with epidemic proportion, and so there is growing interest in finding new drugs from natural and synthetic sources to help halt this epidemic. The book is divided into six sections: the first part addresses fact and figures of diabetes and obesity at global level. In the second part, the physiological control of carbohydrate and lipid metabolism as well as some common therapeutic targets are presented. In section 3, the pathophysiology of type-2 diabetes and therapeutic options are presented. A dedicated section on super fruits include the therapeutic potential of bilberry and blueberries, bitter melon, okra, prickly pear cactus and other fruits that gain importance as antidiabetic agents in recent years. In section 5, the chemistry and pharmacology of spices including cinnamon, cloves, fenugreek, garlic, ginger and turmeric are presented to outline their antidiabetic potential. The last section includes beverages such as tea, coffee and yerba mate as well as a dedicated chapter on food supplements and other food products with emerging antidiabetic potential. Medicinal Foods as Potential Therapies for Type-2 Diabetes: The Chemical and Pharmacological Basis of their Action is invaluable research scientists and students in medical and pharmaceutical sciences, medicinal chemistry, herbal medicine, drug discovery/development, nutrition science as well as herbal practitioners, industries from the nutraceutical and pharmaceutical areas, and organizations dealing with diabetes and obesity managements"--
Dr. Solomon Habtemariam is a Founder/Owner of Herbal Analysis Services UK & Leader of the Pharmacognosy Research Laboratories at the University of Greenwich, Chatham-Maritime, UK. Dr Habtemariam received his BSc degree in Biology (minor - Chemistry) from the University of Addis Ababa and his Master's degree (combined-studies) in Pharmacology and Phytochemistry from the University of Strathclyde, Glasgow, UK. He stayed on at Strathclyde to study at doctoral level, studying on drug discovery researches and obtained his PhD in this area of research. After a number of years in teaching and post-doctoral research at the Strathclyde Institute for Drug Research and Strathclyde University, he joined the School of Science, University of Greenwich in September 1998. Dr Habtemariam has been a leader of taught programmes and researches on bioassays & natural products-based drug development. The various researches that he has undertaken include the identification of novel compounds of natural-origin with potential antimicrobial, anticancer, anti-inflammatory, antidiabetic and antiobesity applications among others. He has published more than 167 scientific publications in peer reviewed journals and filed over three family of patents. He is also the author of a book entitled "The African and Arabian Moringa Species: Chemistry Bioactivity and Therapeutic Applications?. Details of his research activities and publications are available via his URL: http://www.herbalanalysis.co.uk
Inhaltsangabe
Type-2 diabetes: Prevalence and significance 1. Type-2 diabetes: Definition, diagnosis and significance Normal physiological control of carbohydrate and lipid metabolism and some common antidiabetic therapeutic targets 2. Glucose metabolism: Normal physiology, diabetic dysregulation, and therapeutic targets 3. Lipid metabolism: Normal physiology, dysregulation under obesity and diabetes, and therapeutic targets Pathophysiology of type 2 diabetes and therapeutic options 4. Pathophysiology of type 2 diabetes complications 5. Current pharmacotherapy options for type 2 diabetes 6. Introduction to plant secondary metabolites-From biosynthesis to chemistry and antidiabetic action Potential modulators of type-2 diabetes and associated diseases: Super fruits 7. Bilberries and blueberries as potential modulators of type 2 diabetes and associated diseases 8. The chemical and pharmacological basis of bitter melon (Momordica charantia L.) as a potential therapy for type 2 diabetes and obesity 9. The chemical and pharmacological basis of guava (Psidium guajava L.) as potential therapy for type 2 diabetes and associated diseases 10. The chemical and pharmacological basis of okra (Abelmoschus esculentus (L.) Moench) as potential therapy for type 2 diabetes 11. The chemical and pharmacological basis of papaya (Carica papaya L.) as potential therapy for type-2 diabetes and associated diseases 12. The chemical and pharmacological basis of pomegranate (Punica grantum L.) as potential therapy for type-2 diabetes and metabolic syndrome 13. The chemical and pharmacological basis of prickly pear cactus (Opuntia species) as potential therapy for type 2 diabetes and obesity 14. The chemical and pharmacological basis of pumpkins (Cucurbita species) as potential therapy for type-2 diabetes Potential modulators of type-2 diabetes and associated diseases: Spices 15. The chemical and pharmacological basis of cinnamon (Cinnamomum species) as potential therapy for type-2 diabetes and associated diseases 16. The chemical and pharmacological basis of cloves (Syzygium aromaticum (L.) Merr. & L.M.Perry) as potential therapy for type 2 diabetes and associated diseases 17. The chemical and pharmacological basis of fenugreek (Trigonella foenum-graecum L.) as potential therapy for type 2 diabetes and associated diseases 18. The chemical and pharmacological basis of ginger (Zingiber officinale Roscoe) as potential therapy for diabetes and metabolic syndrome 19. The chemical and pharmacological basis of garlic (Allium sativum L.) as potential therapy for type 2 diabetes and metabolic syndrome 20. The chemical and pharmacological basis of turmeric (Curcuma longa L.) as potential therapy for type 2 diabetes and metabolic syndrome Potential modulators of type 2 diabetes and associated diseases: Beverages, other foods, and herbal supplements 21. Chemical and pharmacological evidences for coffee as a modulator of type 2 diabetes and metabolic syndrome 22. The chemical and pharmacological basis of tea (Camellia sinensis (L.) Kuntze) as potential therapy for type 2 diabetes and metabolic syndrome 23. The chemical and pharmacological basis of rooibos (Aspalathus linearis (Burm. F.) R. Dahlgren) as potential therapy for type 2 diabetes and metabolic syndrome 24. The chemical and pharmacological basis of yerba matgrowing importance as antidiabetic agents 26. Antidiabetic herbal medicines rebranded as dietary supplements
Type-2 diabetes: Prevalence and significance 1. Type-2 diabetes: Definition, diagnosis and significance Normal physiological control of carbohydrate and lipid metabolism and some common antidiabetic therapeutic targets 2. Glucose metabolism: Normal physiology, diabetic dysregulation, and therapeutic targets 3. Lipid metabolism: Normal physiology, dysregulation under obesity and diabetes, and therapeutic targets Pathophysiology of type 2 diabetes and therapeutic options 4. Pathophysiology of type 2 diabetes complications 5. Current pharmacotherapy options for type 2 diabetes 6. Introduction to plant secondary metabolites-From biosynthesis to chemistry and antidiabetic action Potential modulators of type-2 diabetes and associated diseases: Super fruits 7. Bilberries and blueberries as potential modulators of type 2 diabetes and associated diseases 8. The chemical and pharmacological basis of bitter melon (Momordica charantia L.) as a potential therapy for type 2 diabetes and obesity 9. The chemical and pharmacological basis of guava (Psidium guajava L.) as potential therapy for type 2 diabetes and associated diseases 10. The chemical and pharmacological basis of okra (Abelmoschus esculentus (L.) Moench) as potential therapy for type 2 diabetes 11. The chemical and pharmacological basis of papaya (Carica papaya L.) as potential therapy for type-2 diabetes and associated diseases 12. The chemical and pharmacological basis of pomegranate (Punica grantum L.) as potential therapy for type-2 diabetes and metabolic syndrome 13. The chemical and pharmacological basis of prickly pear cactus (Opuntia species) as potential therapy for type 2 diabetes and obesity 14. The chemical and pharmacological basis of pumpkins (Cucurbita species) as potential therapy for type-2 diabetes Potential modulators of type-2 diabetes and associated diseases: Spices 15. The chemical and pharmacological basis of cinnamon (Cinnamomum species) as potential therapy for type-2 diabetes and associated diseases 16. The chemical and pharmacological basis of cloves (Syzygium aromaticum (L.) Merr. & L.M.Perry) as potential therapy for type 2 diabetes and associated diseases 17. The chemical and pharmacological basis of fenugreek (Trigonella foenum-graecum L.) as potential therapy for type 2 diabetes and associated diseases 18. The chemical and pharmacological basis of ginger (Zingiber officinale Roscoe) as potential therapy for diabetes and metabolic syndrome 19. The chemical and pharmacological basis of garlic (Allium sativum L.) as potential therapy for type 2 diabetes and metabolic syndrome 20. The chemical and pharmacological basis of turmeric (Curcuma longa L.) as potential therapy for type 2 diabetes and metabolic syndrome Potential modulators of type 2 diabetes and associated diseases: Beverages, other foods, and herbal supplements 21. Chemical and pharmacological evidences for coffee as a modulator of type 2 diabetes and metabolic syndrome 22. The chemical and pharmacological basis of tea (Camellia sinensis (L.) Kuntze) as potential therapy for type 2 diabetes and metabolic syndrome 23. The chemical and pharmacological basis of rooibos (Aspalathus linearis (Burm. F.) R. Dahlgren) as potential therapy for type 2 diabetes and metabolic syndrome 24. The chemical and pharmacological basis of yerba matgrowing importance as antidiabetic agents 26. Antidiabetic herbal medicines rebranded as dietary supplements
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