This unique overview of plants and transgenic techniques of great scientific, medicinal and economic value for both industry and academia covers the whole spectrum from cell culture techniques, via genetic engineering and secondary product metabolism right up to the use of transgenic plants for the production of bioactive compounds. Practical examples are given throughout, including the production of cancer therapeutics, functional food, and flavor compounds in plants.Of particular interest to the pharmaceutical and biotechnological industries, as well as medicinal chemists, biochemists, and molecular biologists.…mehr
This unique overview of plants and transgenic techniques of great scientific, medicinal and economic value for both industry and academia covers the whole spectrum from cell culture techniques, via genetic engineering and secondary product metabolism right up to the use of transgenic plants for the production of bioactive compounds. Practical examples are given throughout, including the production of cancer therapeutics, functional food, and flavor compounds in plants.Of particular interest to the pharmaceutical and biotechnological industries, as well as medicinal chemists, biochemists, and molecular biologists.
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Autorenporträt
Prof. Oliver Kayser studied pharmacy at the University Mnster. He received his PhD and his postdoctoral qualification (Habilitation) from the Free University Berlin in 1997 and 2003. In 2004 he was appointed Assistant Professor at the University Groningen for Pharmaceutical Biology. His research interests are phytochemstry, combinatorial biosynthesis and plant biotechnology. He has published more than 100 peer reviewed papers and proceedings and has authored and edited 5 books.
Professor Wim Quax is head of the laboratory of pharmaceutical biology in the Groningen Research Institute of Pharmacy in the Netherlands. He has published more than 70 peer reviewed papers, and is member of numerous scientific organisations and committees.
Inhaltsangabe
Foreword
Introduction
PART 1 METABOLIC PATHWAYS AND SECONDARY PRODUCTS
Introduction to medicinal plant biotechnology
Proteomics in plant biotechnology and secondary metabolism research and metabolic profiling
LC-NMR/MS as new technique for plant extract screening
High Throughput Screening of plant extracts
Endophytes as new source of natural products
Polyketide pathway and artemisinin
Biotechnology methods for selection of high yielding cell lines and production of secondary metabolite in medicinal plants
PART 2 GENETIC MODIFICATION AND TRANSGENIC PLANTS
Problems and strategies of plant gene tranfer systems
Sequencing of A. thaliana - what can we learn for the future
In vitro manipulation and propagation of medicinal plants
Medicinally used transgenic plants
Proteomics and Bioinformatics on medicinal plant genomes
Combinatorial biosynthesis
Identification of plant species
PART 3 CELL CULTURE AND PRODUCTION OF MEDICINAL PRODUCTS
Production of paclitaxel
Production of heterologous recombinant proteins in plant systems
Biorector techniques for plants
Breeding of transgenic medicinal plants, Resistance
In vitro culturing techniques of medicinal plants
Biotechnology for improving medicinal plants
PART 4 USE OF GENETICALLY MODIFIED MEDICINALLY PLANTS
Regulation of transgenic plant breeding
Functional plants in food industry
Intellectual property protection of plant biotechnology inventions
Industrial perspective of plant biotechnology in medicine
Vaccines produced in plants
Biotechnology of neem : Azadirachta indica A. juss
Biodegradable plastics
Plant biotechnology and the production of flavour compounds
