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The main interest of this Research is ,The use of Medicinal plant extract as alternative to resolve the Disease Resistance Probleme in fish aquaculture. Investigate the effect of the medicinal plant Scutellaria baicalensis extracts (Scutellaria polysaccharides) on plasma biochemical parameters, antioxidant activities, the expression of antioxidant enzymes related genes and immune-related genes on (carassius gibelio) artificially challenged by Aeromonas hydrophila.