Metal Chelation in Medicine

Herausgeber: Crichton, Robert; Hider, Robert C; Ward, Roberta J

• Gebundenes Buch

Produktbeschreibung

Metal chelators are emerging as versatile tools with many medical applications. Chelating agents are capable of binding to toxic metal ions to form complex structures which are easily excreted from the body, removing them from intracellular or extracellular spaces. In addition, metal chelators can be applied as imaging agents in various forms of clinical scanning techniques. Metal Chelation in Medicine provides a clear and timely perspective on the role of chelating agents in the management of metal intoxications and storage diseases. Written by leaders in the field, this book covers a broad range of topics such as the use of metal chelators in non-invasive assessment of brain iron overload, and the treatment of systemic iron overload and neurodegenerative diseases. As such it is particularly valuable to clinicians treating metal poisonings and metal storage diseases. However, it is also a useful text for researchers, industry professionals and university students with a specific interest in medicinal chemistry, chelation, metal ions, imaging and non-invasive techniques.

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Produktdetails

• Verlag: RSC Publishing
• Seitenzahl: 322
• Erscheinungstermin: 26. Oktober 2016
• Englisch
• Abmessung: 236mm x 160mm x 23mm
• Gewicht: 635g
• ISBN-13: 9781782620648
• ISBN-10: 1782620648
• Artikelnr.: 45060525

Inhaltsangabe

Metal toxicity - essential elements/non-essential elements
Non-invasive assessment of brain iron overload
Chelators for imaging
Basic principles of metal chelation and chelation design
Synthetic strategies for therapeutic chelators
Therapeutic applications of chelation therapy
Treatment of systemic iron overload
Treatment of neurodegenerative diseases by chelators
Chelation of actinides, plutonium, uranium