Oral cavity acts as a niche for numerous microorganisms. Among them ,some are pathogenic and cause infections. Hence to control and prevent such infections, a lot of researches are conducted on different materials using various advanced techniques. Nanotechnology and nanoscience have emerged in the recent years exploring the antimicrobial effects of metal nanoparticles. Distinct physical, biologic and chemical properties of metallic oxide nanoparticles make them efficient antimicrobial agents . Application of this nanotechnology in dentistry termed as Nanodentistry, has brought many effective changes in the dental materials .