Methodologies for Metabolomics
Experimental Strategies and Techniques
Herausgeber: Lutz, Norbert; Wevers, Ron; Sweedler, Jonathan
Methodologies for Metabolomics
Experimental Strategies and Techniques
Herausgeber: Lutz, Norbert; Wevers, Ron; Sweedler, Jonathan
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Methodologies for Metabolomics provides comprehensive descriptions of the newest methodological strategies and techniques in metabolomic research.
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Methodologies for Metabolomics provides comprehensive descriptions of the newest methodological strategies and techniques in metabolomic research.
Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Produktdetails
- Produktdetails
- Verlag: Cambridge University Press
- Seitenzahl: 640
- Erscheinungstermin: 27. Februar 2014
- Englisch
- Abmessung: 260mm x 183mm x 39mm
- Gewicht: 1380g
- ISBN-13: 9780521765909
- ISBN-10: 0521765900
- Artikelnr.: 36126358
- Verlag: Cambridge University Press
- Seitenzahl: 640
- Erscheinungstermin: 27. Februar 2014
- Englisch
- Abmessung: 260mm x 183mm x 39mm
- Gewicht: 1380g
- ISBN-13: 9780521765909
- ISBN-10: 0521765900
- Artikelnr.: 36126358
List of contributors; Part I. Basic Methodological Strategies in
Metabolomic Research: 1. Exploring the human metabolome by nuclear magnetic
resonance spectroscopy and mass spectroscopy; 2. Methodological
requirements for lipidomics research; 3. Biological methods for metabolic
research; Part II. Metabolomic Mass Spectrometry: Experimental Techniques
and Bioinformatics: 4. Considerations in sample preparation, collection,
and extraction approaches applied in microbial, plant, and mammalian
metabolic profiling; 5. Mass spectrometry-based methodologies for
single-cell metabolite detection and identification; 6. Direct metabolomics
from tissues and cells: laser ablation electrospray ionization for small
molecule and lipid characterization; 7. Bioinformatic approaches to
processing and annotation of high-resolution mass spectrometry data; 8.
Approaches for natural product detection and structural elucidation using
mass spectrometry with high mass accuracy; 9. Metabolomics using ion
mobility mass spectrometry; 10. Metabolomics via biomedical mass
spectrometry: from sampling to clinical applications; Part III.
Metabolomics of Biofluids: Nuclear Magnetic Resonance Spectroscopy and
Chemometrics: 11. Analytical techniques in metabolomics integrating nuclear
magnetic resonance spectroscopy and chromatography with mass spectrometry;
12. Chemometric methods in nuclear magnetic resonance-based body fluid
analysis; 13. Nuclear magnetic resonance of cerebrospinal fluid: the
neurometabolome; 14. Nuclear magnetic resonance-based saliva metabolomics;
15. Nuclear magnetic resonance methods for metabolomic investigation of
amniotic fluid; 16. Nuclear magnetic resonance analysis and genetic
metabolic disease; 17. Lipid profiling in health and disease; Part IV.
Metabolomic Nuclear Magnetic Resonance Spectroscopy Techniques for Body
Tissue Analysis: 18. Magnetic resonance spectroscopy in investigating the
cancer metabolome in preclinical model systems; 19. Phospholipidomics by
phosphorous nuclear magnetic resonance spectroscopy of tissue extracts; 20.
Carbon-13 nuclear magnetic resonance for analysis of metabolic pathways;
21. Hyperpolarized nuclear magnetic resonance spectroscopy - a new method
for metabolomic research; 22. Metabolomic magnetic resonance spectroscopy
of human tissues: comparison of in vivo and high-resolution magic angle
spinning ex vivo techniques; 23. Reproducible sample preparation and
spectrum acquisition techniques for metabolic profiling of human tissues by
proton high-resolution magic angle spinning nuclear magnetic resonance; 24.
Assignment strategies for nuclear magnetic resonances in metabolomics
research; Index.
Metabolomic Research: 1. Exploring the human metabolome by nuclear magnetic
resonance spectroscopy and mass spectroscopy; 2. Methodological
requirements for lipidomics research; 3. Biological methods for metabolic
research; Part II. Metabolomic Mass Spectrometry: Experimental Techniques
and Bioinformatics: 4. Considerations in sample preparation, collection,
and extraction approaches applied in microbial, plant, and mammalian
metabolic profiling; 5. Mass spectrometry-based methodologies for
single-cell metabolite detection and identification; 6. Direct metabolomics
from tissues and cells: laser ablation electrospray ionization for small
molecule and lipid characterization; 7. Bioinformatic approaches to
processing and annotation of high-resolution mass spectrometry data; 8.
Approaches for natural product detection and structural elucidation using
mass spectrometry with high mass accuracy; 9. Metabolomics using ion
mobility mass spectrometry; 10. Metabolomics via biomedical mass
spectrometry: from sampling to clinical applications; Part III.
Metabolomics of Biofluids: Nuclear Magnetic Resonance Spectroscopy and
Chemometrics: 11. Analytical techniques in metabolomics integrating nuclear
magnetic resonance spectroscopy and chromatography with mass spectrometry;
12. Chemometric methods in nuclear magnetic resonance-based body fluid
analysis; 13. Nuclear magnetic resonance of cerebrospinal fluid: the
neurometabolome; 14. Nuclear magnetic resonance-based saliva metabolomics;
15. Nuclear magnetic resonance methods for metabolomic investigation of
amniotic fluid; 16. Nuclear magnetic resonance analysis and genetic
metabolic disease; 17. Lipid profiling in health and disease; Part IV.
Metabolomic Nuclear Magnetic Resonance Spectroscopy Techniques for Body
Tissue Analysis: 18. Magnetic resonance spectroscopy in investigating the
cancer metabolome in preclinical model systems; 19. Phospholipidomics by
phosphorous nuclear magnetic resonance spectroscopy of tissue extracts; 20.
Carbon-13 nuclear magnetic resonance for analysis of metabolic pathways;
21. Hyperpolarized nuclear magnetic resonance spectroscopy - a new method
for metabolomic research; 22. Metabolomic magnetic resonance spectroscopy
of human tissues: comparison of in vivo and high-resolution magic angle
spinning ex vivo techniques; 23. Reproducible sample preparation and
spectrum acquisition techniques for metabolic profiling of human tissues by
proton high-resolution magic angle spinning nuclear magnetic resonance; 24.
Assignment strategies for nuclear magnetic resonances in metabolomics
research; Index.
List of contributors; Part I. Basic Methodological Strategies in
Metabolomic Research: 1. Exploring the human metabolome by nuclear magnetic
resonance spectroscopy and mass spectroscopy; 2. Methodological
requirements for lipidomics research; 3. Biological methods for metabolic
research; Part II. Metabolomic Mass Spectrometry: Experimental Techniques
and Bioinformatics: 4. Considerations in sample preparation, collection,
and extraction approaches applied in microbial, plant, and mammalian
metabolic profiling; 5. Mass spectrometry-based methodologies for
single-cell metabolite detection and identification; 6. Direct metabolomics
from tissues and cells: laser ablation electrospray ionization for small
molecule and lipid characterization; 7. Bioinformatic approaches to
processing and annotation of high-resolution mass spectrometry data; 8.
Approaches for natural product detection and structural elucidation using
mass spectrometry with high mass accuracy; 9. Metabolomics using ion
mobility mass spectrometry; 10. Metabolomics via biomedical mass
spectrometry: from sampling to clinical applications; Part III.
Metabolomics of Biofluids: Nuclear Magnetic Resonance Spectroscopy and
Chemometrics: 11. Analytical techniques in metabolomics integrating nuclear
magnetic resonance spectroscopy and chromatography with mass spectrometry;
12. Chemometric methods in nuclear magnetic resonance-based body fluid
analysis; 13. Nuclear magnetic resonance of cerebrospinal fluid: the
neurometabolome; 14. Nuclear magnetic resonance-based saliva metabolomics;
15. Nuclear magnetic resonance methods for metabolomic investigation of
amniotic fluid; 16. Nuclear magnetic resonance analysis and genetic
metabolic disease; 17. Lipid profiling in health and disease; Part IV.
Metabolomic Nuclear Magnetic Resonance Spectroscopy Techniques for Body
Tissue Analysis: 18. Magnetic resonance spectroscopy in investigating the
cancer metabolome in preclinical model systems; 19. Phospholipidomics by
phosphorous nuclear magnetic resonance spectroscopy of tissue extracts; 20.
Carbon-13 nuclear magnetic resonance for analysis of metabolic pathways;
21. Hyperpolarized nuclear magnetic resonance spectroscopy - a new method
for metabolomic research; 22. Metabolomic magnetic resonance spectroscopy
of human tissues: comparison of in vivo and high-resolution magic angle
spinning ex vivo techniques; 23. Reproducible sample preparation and
spectrum acquisition techniques for metabolic profiling of human tissues by
proton high-resolution magic angle spinning nuclear magnetic resonance; 24.
Assignment strategies for nuclear magnetic resonances in metabolomics
research; Index.
Metabolomic Research: 1. Exploring the human metabolome by nuclear magnetic
resonance spectroscopy and mass spectroscopy; 2. Methodological
requirements for lipidomics research; 3. Biological methods for metabolic
research; Part II. Metabolomic Mass Spectrometry: Experimental Techniques
and Bioinformatics: 4. Considerations in sample preparation, collection,
and extraction approaches applied in microbial, plant, and mammalian
metabolic profiling; 5. Mass spectrometry-based methodologies for
single-cell metabolite detection and identification; 6. Direct metabolomics
from tissues and cells: laser ablation electrospray ionization for small
molecule and lipid characterization; 7. Bioinformatic approaches to
processing and annotation of high-resolution mass spectrometry data; 8.
Approaches for natural product detection and structural elucidation using
mass spectrometry with high mass accuracy; 9. Metabolomics using ion
mobility mass spectrometry; 10. Metabolomics via biomedical mass
spectrometry: from sampling to clinical applications; Part III.
Metabolomics of Biofluids: Nuclear Magnetic Resonance Spectroscopy and
Chemometrics: 11. Analytical techniques in metabolomics integrating nuclear
magnetic resonance spectroscopy and chromatography with mass spectrometry;
12. Chemometric methods in nuclear magnetic resonance-based body fluid
analysis; 13. Nuclear magnetic resonance of cerebrospinal fluid: the
neurometabolome; 14. Nuclear magnetic resonance-based saliva metabolomics;
15. Nuclear magnetic resonance methods for metabolomic investigation of
amniotic fluid; 16. Nuclear magnetic resonance analysis and genetic
metabolic disease; 17. Lipid profiling in health and disease; Part IV.
Metabolomic Nuclear Magnetic Resonance Spectroscopy Techniques for Body
Tissue Analysis: 18. Magnetic resonance spectroscopy in investigating the
cancer metabolome in preclinical model systems; 19. Phospholipidomics by
phosphorous nuclear magnetic resonance spectroscopy of tissue extracts; 20.
Carbon-13 nuclear magnetic resonance for analysis of metabolic pathways;
21. Hyperpolarized nuclear magnetic resonance spectroscopy - a new method
for metabolomic research; 22. Metabolomic magnetic resonance spectroscopy
of human tissues: comparison of in vivo and high-resolution magic angle
spinning ex vivo techniques; 23. Reproducible sample preparation and
spectrum acquisition techniques for metabolic profiling of human tissues by
proton high-resolution magic angle spinning nuclear magnetic resonance; 24.
Assignment strategies for nuclear magnetic resonances in metabolomics
research; Index.