Bassam Ayoub, Ramzia El-bagary, Ehab Elkady

Methods of Determination of Some Oral Hypoglycemic Drugs

• Broschiertes Buch

Produktbeschreibung

Different methods for determination of some oral hypoglycemic drugs have been introduced in this book. These drugs are alogliptin benzoate, linagliptin, metformin hydrochloride, saxagliptin hydrochloride, sitagliptin phosphate, and vildagliptin. Chromatographic part included determination of sitagliptin phosphate in bulk and in plasma using fluorimetric detection in the presence of sitagliptin acid degradation product after its preparation and structure elucidation and in its ternay mixture with metformin hydrochloride and sitagliptin acid degradation product using ultraviolet detection. Besides, simultaneous determination of each of three novel gliptins; sitagliptin phosphate, vildagliptin, saxagliptin hydrochloride and metformin hydrochloride in the presence of metformin impurity (cyanoguanidine) was developed. And determination of linagliptin using ultraviolet detection and fluorimetric detection was also developed. Simultaneous determination of linagliptin and metformin hydrochloride and determination of alogliptin benzoate using ultraviolet detection was also developed.

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Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Seitenzahl: 200
• Erscheinungstermin: 28. Juni 2016
• Englisch
• Abmessung: 220mm x 150mm x 12mm
• Gewicht: 316g
• ISBN-13: 9783659913402
• ISBN-10: 3659913405
• Artikelnr.: 45478861

Autorenporträt

Bassam Ayoub, PhD in Pharmaceutical analysis from the Faculty of Pharmacy, Cairo University. Lecturer of Chemistry, British University in Egypt.