Metronidazole co-crystals - Allal, Farida;HELIFA, FATIMA ZOHRA;LAMRI, KHADIDJA
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Strategies commonly used to improve the therapeutic effect and antibacterial activity of active pharmaceutical ingredients involve exploring their solid forms, notably polymorphs, solvates/hydrates, salts and cocrystals. Among the various approaches considered to remedy the problem of bacterial resistance, the strategy of co-crystallization of antibiotics with coformers appears to be a promising solution for improving physicochemical properties, inhibiting resistance and enhancing antibacterial activity.

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Produktbeschreibung
Strategies commonly used to improve the therapeutic effect and antibacterial activity of active pharmaceutical ingredients involve exploring their solid forms, notably polymorphs, solvates/hydrates, salts and cocrystals. Among the various approaches considered to remedy the problem of bacterial resistance, the strategy of co-crystallization of antibiotics with coformers appears to be a promising solution for improving physicochemical properties, inhibiting resistance and enhancing antibacterial activity.
Autorenporträt
Doktor ALLAL Farida, prepodawatel' i nauchnyj sotrudnik Uniwersiteta Amar Telidli, Laguat, Alzhir. Oblast' moih interesow - termodinamika i ee primenenie k binarnym i mnogokomponentnym smesqm, a takzhe ocenka mezhmolekulqrnyh wzaimodejstwij w binarnyh kombinaciqh aktiwnyh ingredientow.