Birte Steiniger, Peter Barth

Microanatomy and Function of the Spleen

• Broschiertes Buch

Produktbeschreibung

5 Function of Splenic Compartments . . . . . . . . . . . . . . . 45 5. 1 Splenic White Pulp Compartments during Primary T Cell-Dependent Antibody Responses against Protein Antigens . . . . . . . . . . . . . . . . . . . . . . . . . 46 5. 1. 1 Priming of CD4+ Helper T Cells by Dendritic Cells in the PALS . . . . . . . . . . . . . . . . . . . . 46 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 5. 1. 1. 1 5. 1. 2 Interaction of Primed CD4+ T Cells with Antigen-Specific B Cells in the PALS and Formation of Extrafollicular Foci . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 5. 1. 2. 1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 5. 1. 3 Formation of Germinal Centres . . . . . . . . . . . . . . . . . . . 50 5. 1. 3. 1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55 5. 1. 4 Localisation of Memory B Cells in the Marginal Zone . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55 5. 1. 4. 1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 5. 2 Function of the Marginal Zone during Primary Antibody Responses against T Cell-Independent Type 2 Antigens . . . . . . . . 57 5. 2. 1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59 Function of the Red Pulp . . . . . . . . . . . . . . . . . . . . . . . . . 59 5. 3 5. 3. 1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61 5. 4 Role of the Spleen in CD8+ Cytotoxic T Cell Responses . . . . . . . . . . . . . . . 61 5. 4. 1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62 The Spleen, Natural Killer Cells 5. 5 and Gamma/Delta T Cells . . . . . . . . . . . . . . .. . . . . . . . . 62 5. 5. 1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63 6 Recirculation of Lymphocytes Through the Spleen . . 65 6. 1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67 7 The Role of Cytokines and Chemokines in the Development of Splenic Compartments . . . . . . 69 7. 1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72 8 Unsolved Problems of Human Splenic Structure and Function . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73 VI 8. 1 Arterial Blood Supply to the Splenic Follicles and to the Perifollicular Zone. . . . . . . . . . . . . . . . . 73 . . . . 8. 1. 1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74 8.

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Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.

Produktdetails

• Advances in Anatomy, Embryology and Cell Biology Vol.151
• Verlag: Springer / Springer Berlin Heidelberg / Springer, Berlin
• Artikelnr. des Verlages: 978-3-540-66161-0
• Softcover reprint of the original 1st ed. 1999
• Seitenzahl: 112
• Erscheinungstermin: 20. September 1999
• Englisch
• Abmessung: 235mm x 155mm x 7mm
• Gewicht: 202g
• ISBN-13: 9783540661610
• ISBN-10: 3540661611
• Artikelnr.: 23512220

Inhaltsangabe

1 Introduction.- 2 Materials and Methods.- 2.1 Animal Spleens.- 2.2 Human Spleens.- 2.3 Antibodies.- 2.4 Single Staining Procedure for Immunohistology.- 2.5 Double Staining Procedure for Immunohistology.- 2.6 Demonstration of Acid Phosphatase in Cryostat Sections.- 2.7 Demonstration of Alkaline Phosphatase in Cryostat Sections.- 3 Microanatomical Compartments of the Rat Spleen.- 3.1 White Pulp.- 3.2 Red Pulp and Splenic Vessels.- 3.3 Summary.- 4 Microanatomical Compartments of the Human Spleen.- 4.1 White Pulp.- 4.2 Red Pulp and Splenic Vessels.- 4.3 Summary.- 5 Function of Splenic Compartments.- 5.1 Splenic White Pulp Compartments during Primary T Cell-Dependent Antibody Responses against Protein Antigens.- 5.2 Function of the Marginal Zone during Primary Antibody Responses against T Cell-Independent Type 2 Antigens.- 5.3 Function of the Red Pulp.- 5.4 Role of the Spleen in CD8+ Cytotoxic T Cell Responses.- 5.5 The Spleen, Natural Killer Cells and Gamma/Delta T Cells.- 6 Recirculation of Lymphocytes Through the Spleen.- 6.1 Summary.- 7 The Role of Cytokines and Chemokines in the Development of Splenic Compartments.- 7.1 Summary.- 8 Unsolved Problems of Human Splenic Structure and Function.- 8.1 Arterial Blood Supply to the Splenic Follicles and to the Perifollicular Zone.- 8.2 Blood Circulation in the Splenic Red Pulp: Subpopulations of Fibroblasts and their Role.- 8.3 Function of Sheathed Capillaries.- 8.4 Lymphocyte Migration in the Human Splenic White Pulp - A Hypothesis.- 9 Summary.- References.