Microbial production: From genome design to cell surface engineering affords a comprehensive review of novel technology and approaches being implemented for manufacturing microorganisms, written by specialists in both academia and industry. This book is divided into three sections: the first includes technology for improvement of fermentation strains and many supporting technologies and information; the second examines novel technology useful for analysis of cell activities, analyzing gene function, and designing genomes of producer strains; and finally, a discussion of the practical…mehr
Microbial production: From genome design to cell surface engineering affords a comprehensive review of novel technology and approaches being implemented for manufacturing microorganisms, written by specialists in both academia and industry. This book is divided into three sections: the first includes technology for improvement of fermentation strains and many supporting technologies and information; the second examines novel technology useful for analysis of cell activities, analyzing gene function, and designing genomes of producer strains; and finally, a discussion of the practical application of the techniques and success case studies in many fields of bio-production, such as microbiological production, pharmaceuticals, chemicals, foods and cosmetics.
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Autorenporträt
Hideharu Anazawa, Ph.D., Director, Japan Bioindustry Association Sakayu Shimizu, Ph.D., Professor, Kyoto Gakuen University
Inhaltsangabe
Preface.- Part1: Minimum Genome Factory.- Chapter1Creation of novel technology for extracellular protein production towards the development of Bacillus subtilis genome factories.- Chapter2 Minimum genome factories in Schizosaccharomyces pombe.- Chapter3 Minimum genome Factrotry of E. coli.- Part 2: Whole Genome Manipulation for Genome Design.- Chapetr4 Efficient and accurate production of de novo designed gene clusters of large size by a novel Bacillus subtilis based BGM system.- Chapter5 Development and application of novel genome technology in Saccharomyces cerevisiae.- Chapter6 Genome design of Actinomycetes for secondary metabolism.- Part 3: Application of Omics Information and Construction of Mutant Libraries.- Chapter7 Application methodology of whole omics information.- Chapter8 Application of Genomics in molecular breeding of the koji molds Aspergillus oryzae and Aspergillus sojae.- Chapter9 Comprehensive libraries of Escherichia coli K-12 and their application.- Chapter10 Insights into metabolism and the galactose recognition system from microarray analysis in the fission yeast Schizosaccharomyces pombe.- Part 4: Applications of Advanced Technologies for Production.- Chapter11 Multi-enzymatic systems for the production of chemical compounds.- Chapter12 Use of organic solvent tolerant microorganisms in bioconversion.- Chapter13 Approaches for improving protein production by cell surface engineering.- Chapter14 Strategies for increasing the production level of heterologous proteins in Aspergillus oryzae.- Chapter15 Overproduction of L- Glutamate in Corynebacterium glutamicum.- Part 5: Pharmaceuticals.- Chapter16 Microbial hormones as a master switch for secondary metabolism in Streptomyces.- Chapter17 Enzymatic production of designed peptide.- Part 6: Functional Foods.- Chapter18 Microbial production of functional polyunsaturated fatty acids and their derivatives.- Chapter19 Enzymatic production of Oligosaccharides.- Part 7: Cosmetics.- Chapter20 Cosmetic Ingredients Fermented by Lactic Acid Bacteria.- Chapter21 Structure of tyrosinase and its inhibitor from sake lees.- Part 8: Energy and Chemicals.- Chapter22 Towards realization of new biorefinery industries using Corynebacterium glutamicum.- Chapter23 Hydrogen Production Using Photosynthetic Bacteria.- Chapter24 Production of biofuels and useful materials by anaerobic organisms in ecosystem of methane fermentation.
Preface.- Part1: Minimum Genome Factory.- Chapter1Creation of novel technology for extracellular protein production towards the development of Bacillus subtilis genome factories.- Chapter2 Minimum genome factories in Schizosaccharomyces pombe.- Chapter3 Minimum genome Factrotry of E. coli.- Part 2: Whole Genome Manipulation for Genome Design.- Chapetr4 Efficient and accurate production of de novo designed gene clusters of large size by a novel Bacillus subtilis based BGM system.- Chapter5 Development and application of novel genome technology in Saccharomyces cerevisiae.- Chapter6 Genome design of Actinomycetes for secondary metabolism.- Part 3: Application of Omics Information and Construction of Mutant Libraries.- Chapter7 Application methodology of whole omics information.- Chapter8 Application of Genomics in molecular breeding of the koji molds Aspergillus oryzae and Aspergillus sojae.- Chapter9 Comprehensive libraries of Escherichia coli K-12 and their application.- Chapter10 Insights into metabolism and the galactose recognition system from microarray analysis in the fission yeast Schizosaccharomyces pombe.- Part 4: Applications of Advanced Technologies for Production.- Chapter11 Multi-enzymatic systems for the production of chemical compounds.- Chapter12 Use of organic solvent tolerant microorganisms in bioconversion.- Chapter13 Approaches for improving protein production by cell surface engineering.- Chapter14 Strategies for increasing the production level of heterologous proteins in Aspergillus oryzae.- Chapter15 Overproduction of L- Glutamate in Corynebacterium glutamicum.- Part 5: Pharmaceuticals.- Chapter16 Microbial hormones as a master switch for secondary metabolism in Streptomyces.- Chapter17 Enzymatic production of designed peptide.- Part 6: Functional Foods.- Chapter18 Microbial production of functional polyunsaturated fatty acids and their derivatives.- Chapter19 Enzymatic production of Oligosaccharides.- Part 7: Cosmetics.- Chapter20 Cosmetic Ingredients Fermented by Lactic Acid Bacteria.- Chapter21 Structure of tyrosinase and its inhibitor from sake lees.- Part 8: Energy and Chemicals.- Chapter22 Towards realization of new biorefinery industries using Corynebacterium glutamicum.- Chapter23 Hydrogen Production Using Photosynthetic Bacteria.- Chapter24 Production of biofuels and useful materials by anaerobic organisms in ecosystem of methane fermentation.
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