Microbial Synthetic Biology

Volume 40

• Gebundenes Buch

Produktbeschreibung

The 40th volume of Methods in Microbiology focuses on microbial synthetic biology.Synthetic biology is a rapidly growing discipline that builds on well-established principles of genetic engineering and biotechnology by integrating computational and engineering approaches to the design and construction of novel biological systems.This volume addresses some of the major technical challenges stand in the way of achieving a radical step-change in our ability to engineer complex multi-scaled biological systems. These include: the application of computation intelligence to the design of synthetic microbial systems, design automation and constraints; the impact of noise and stochasticity; the engineering of biosensors; the characteristic of a model bacterial chassis. A key issue in Synthetic Biology is that of its social dimensions and a chapter is dedicated to the important issue.

Produktdetails

• Verlag: Elsevier Health Sciences
• Seitenzahl: 240
• Erscheinungstermin: 9. Dezember 2013
• Englisch
• Abmessung: 241mm x 192mm x 22mm
• Gewicht: 629g
• ISBN-13: 9780124170292
• ISBN-10: 0124170293
• Artikelnr.: 39171614

Inhaltsangabe

1. Computational Intelligence in the Design of Synthetic Microbial Genetic
SystemsJennifer S. Hallinan2. Constraints in the Design of the Synthetic
Bacterial ChassisAntoine Danchin and Agnieszka Sekowska3. Social Dimensions
of Microbial Synthetic BiologyJane Calvert and Emma Frow4. Bacillus
Subtilis: Model Gram-positive Synthetic Biology ChassisColin R. Harwood,
Suzanne Pohl, Wendy Smith and Anil Wipat5. Engineering Microbial Biosensors
Lisa Goers, Nicolas Kylilis, Marios Tomazou, Ke Yan Wen, Paul Freemont and
Karen Polizzi6. Noise and Stochasticity in Gene Expression - A Pathogenic
Fate determinantMikkel Girke Jørgensen, Renske van Raaphorst and Jan-Willem
Veening7. Platforms for Genetic Design AutomationChris J. Myers