Microrna in Human Malignancies

Herausgeber: Negrini, Massimo; Croce, Carlo M; Calin, George A

• Broschiertes Buch

Produktbeschreibung

MicroRNA in Human Malignancies offers a deep overview of the role and translational significance of miRNAs in the development of cancer and other malignancies. The book establishes the foundations of the field by covering essential mechanisms and the translational potential of miRNAs in the field of oncology. Specific topics covered include invasion and metastasis, miRNAs and metabolism, and opportunities of miRNAs in therapeutics. Chapters on diseases include content on disease-related pathophysiology, as well as diagnostic, prognostic and predictive value. This book is an essential reference for students entering the field, as well as researchers and investigators.

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Produktdetails

• Verlag: Elsevier Science
• Seitenzahl: 432
• Erscheinungstermin: 17. Februar 2022
• Englisch
• Abmessung: 235mm x 191mm
• Gewicht: 1220g
• ISBN-13: 9780128222874
• ISBN-10: 0128222875
• Artikelnr.: 62227936

Inhaltsangabe

SECTION 1: miRNAs involvement in basic mechanisms of cancer development 1.
Overview on miRNA classification, biogenesis, and functions 2. microRNA in
cancer: overview 3. miR-15/16 in human malignancies 4. microRNAs and TP53
regulation 5. microRNAs involvement in Invasion and metastasis 6. microRNAs
and metabolism 7. microRNAs in inflammation processes
SECTION 2: miRNAs methodologies 8. Wet-lab methods for miRNA analysis 9.
Bioinformatics utilities, web resources and integrative strategies for the
analysis of miRNA regulatory networks 10. Computational Resources for
Analysis of miRNA Targetome 11. miRNA bioinformatics and pathway analysis
SECTION 3: miRNAs involvement in therapeutics / theranostics 12.
Opportunities of miRNAs in cancer therapeutics
SECTION 4: miRNAs involvement in human cancer: pathophysiology and
translational opportunities 13. Pathophysiology roles and translational
opportunities of miRNAs in acute leukemias 14. Pathophysiology roles and
translational opportunities of miRNAs in CLL 15. Pathophysiology roles and
translational opportunities of miRNAs in Lymphoma 16. Pathophysiology roles
and translational opportunities of miRNAs in Breast cancer 17.
Pathophysiology roles and translational opportunities of miRNAs in
colorectal cancer 18. Pathophysiology roles and translational opportunities
of miRNAs in Lung cancer 19. Pathophysiology roles and translational
opportunities of miRNAs in Mesothelioma 20. Pathophysiology roles and
translational opportunities of miRNAs in Renal cancer 21. Pathophysiology
roles and translational opportunities of miRNAs in Pancreatic cancer 22.
Pathophysiology roles and translational opportunities of miRNAs in Prostate
cancer 23. Pathophysiology roles and translational opportunities of miRNAs
in Hepatocarcinoma 24. Pathophysiology roles and translational
opportunities of miRNAs in Ovarian cancer 25. Pathophysiology roles and
translational opportunities of miRNAs in Bladder cancer 26. Pathophysiology
roles and translational opportunities of miRNAs in Cutaneous Melanoma 27.
Pathophysiology roles and translational opportunities of miRNAs in Brain
tumors 28. Pathophysiology roles and translational opportunities of miRNAs
in Sarcomas