Micrornas
From Basic Science to Disease Biology
Herausgeber: Appasani, Krishnarao; Krishnarao, Appasani
Micrornas
From Basic Science to Disease Biology
Herausgeber: Appasani, Krishnarao; Krishnarao, Appasani
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A wide-ranging reference on microRNA technology, integrating basic science with applications in biotechnology and pharmaceutical industry.
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A wide-ranging reference on microRNA technology, integrating basic science with applications in biotechnology and pharmaceutical industry.
Produktdetails
- Produktdetails
- Verlag: Cambridge University Press
- Seitenzahl: 580
- Erscheinungstermin: 11. Mai 2009
- Englisch
- Abmessung: 254mm x 178mm x 31mm
- Gewicht: 1076g
- ISBN-13: 9780521118552
- ISBN-10: 0521118557
- Artikelnr.: 27006976
- Verlag: Cambridge University Press
- Seitenzahl: 580
- Erscheinungstermin: 11. Mai 2009
- Englisch
- Abmessung: 254mm x 178mm x 31mm
- Gewicht: 1076g
- ISBN-13: 9780521118552
- ISBN-10: 0521118557
- Artikelnr.: 27006976
Foreword
Foreword
Introduction Part I. Discovery of MicroRNAs in Various Organisms: 1. The microRNAs of C. elegans
2. Non-coding RNAs - development of man-made vector-based intronic microRNAs
3. Seeing is believing: strategies for studying microRNA expression
4. MicroRNAs in limb development
5. Identification of miRNAs in plant oryza sativa
Part II. MicroRNA Functions and RNAi-Mediated Pathways: 6. Inhibition of translation initiation by a microRNA
7. In situ analysis of microRNA expression during vertebrate development
8. MicroRNA function in the nervous system
9. Micro RNA expression that controls the amount of branched chain ¿-ketoacid dehydrogenase in mitochondria of human cells
10. MicroRNAs and the regulation of leaf shape
Part III. Computational Biology of MicroRNAs: 11. MiRBase: a database of microRNA sequences, targets and nomenclature
12. Computational prediction of microRNA targets in vertebrates, fruitflies and nematodes
13. Computational approaches to elucidate miRNA biology
14. The RNA hybrid approach to microRNA target prediction
15. Machine learning predicts microRNA target sites
16. Models of microRNA-target coordination
Part IV. Detection and Quantitation of MicroRNAs: 17. Detection and analysis of microRNAs using LNA (locked nucleic acid)-modified probes
18. Detection and quantitation of microRNAs using the RNA Invader® assay
19. A single molecule method to quantify miRNA gene expression
20. Real-time quantification of MicroRNAs by TaqMan® assays
21. Real-time quantification of miRNAs and mRNAs employing universal reverse transcription
Part V. MicroRNAs in Disease Biology: 22. Dysregulation of microRNAs in human malignancy
23. High throughput microRNAs profiling in cancers
24. Roles of microRNAs in cancer and development
25. MiR-122 in mammalian liver
26. MiRNAs in glioblastoma
27. Role of microRNA pathway in Fragile X mental retardation
28. Insertion of miRNA125b-1 into immunoglobulin heavy chain gene locus mediated by V(D)J recombination in precursor B cell acute lymphoblastic leukemia
29. MiRNAs in TPA-induced differentiation of HL-60 cells
30. MiRNAs in skeletal muscle differentiation
31. Identification and potential function of viral microRNAs
32. Lost in translation: regulation of HIV-1 by microRNAs and a key enzyme of RNA-directed RNA polymerase
Part VI. MicroRNAs in Stem Cell Development: 33. MicroRNAs in the stem cells of the mouse Blastocyst
34. The role of miRNA in hematopoiesis
35. MicroRNAs in embryonic stem cell differentiation and prediction of their targets
36. Generation of single cell microRNA expression profile.
Foreword
Introduction Part I. Discovery of MicroRNAs in Various Organisms: 1. The microRNAs of C. elegans
2. Non-coding RNAs - development of man-made vector-based intronic microRNAs
3. Seeing is believing: strategies for studying microRNA expression
4. MicroRNAs in limb development
5. Identification of miRNAs in plant oryza sativa
Part II. MicroRNA Functions and RNAi-Mediated Pathways: 6. Inhibition of translation initiation by a microRNA
7. In situ analysis of microRNA expression during vertebrate development
8. MicroRNA function in the nervous system
9. Micro RNA expression that controls the amount of branched chain ¿-ketoacid dehydrogenase in mitochondria of human cells
10. MicroRNAs and the regulation of leaf shape
Part III. Computational Biology of MicroRNAs: 11. MiRBase: a database of microRNA sequences, targets and nomenclature
12. Computational prediction of microRNA targets in vertebrates, fruitflies and nematodes
13. Computational approaches to elucidate miRNA biology
14. The RNA hybrid approach to microRNA target prediction
15. Machine learning predicts microRNA target sites
16. Models of microRNA-target coordination
Part IV. Detection and Quantitation of MicroRNAs: 17. Detection and analysis of microRNAs using LNA (locked nucleic acid)-modified probes
18. Detection and quantitation of microRNAs using the RNA Invader® assay
19. A single molecule method to quantify miRNA gene expression
20. Real-time quantification of MicroRNAs by TaqMan® assays
21. Real-time quantification of miRNAs and mRNAs employing universal reverse transcription
Part V. MicroRNAs in Disease Biology: 22. Dysregulation of microRNAs in human malignancy
23. High throughput microRNAs profiling in cancers
24. Roles of microRNAs in cancer and development
25. MiR-122 in mammalian liver
26. MiRNAs in glioblastoma
27. Role of microRNA pathway in Fragile X mental retardation
28. Insertion of miRNA125b-1 into immunoglobulin heavy chain gene locus mediated by V(D)J recombination in precursor B cell acute lymphoblastic leukemia
29. MiRNAs in TPA-induced differentiation of HL-60 cells
30. MiRNAs in skeletal muscle differentiation
31. Identification and potential function of viral microRNAs
32. Lost in translation: regulation of HIV-1 by microRNAs and a key enzyme of RNA-directed RNA polymerase
Part VI. MicroRNAs in Stem Cell Development: 33. MicroRNAs in the stem cells of the mouse Blastocyst
34. The role of miRNA in hematopoiesis
35. MicroRNAs in embryonic stem cell differentiation and prediction of their targets
36. Generation of single cell microRNA expression profile.
Foreword
Foreword
Introduction Part I. Discovery of MicroRNAs in Various Organisms: 1. The microRNAs of C. elegans
2. Non-coding RNAs - development of man-made vector-based intronic microRNAs
3. Seeing is believing: strategies for studying microRNA expression
4. MicroRNAs in limb development
5. Identification of miRNAs in plant oryza sativa
Part II. MicroRNA Functions and RNAi-Mediated Pathways: 6. Inhibition of translation initiation by a microRNA
7. In situ analysis of microRNA expression during vertebrate development
8. MicroRNA function in the nervous system
9. Micro RNA expression that controls the amount of branched chain ¿-ketoacid dehydrogenase in mitochondria of human cells
10. MicroRNAs and the regulation of leaf shape
Part III. Computational Biology of MicroRNAs: 11. MiRBase: a database of microRNA sequences, targets and nomenclature
12. Computational prediction of microRNA targets in vertebrates, fruitflies and nematodes
13. Computational approaches to elucidate miRNA biology
14. The RNA hybrid approach to microRNA target prediction
15. Machine learning predicts microRNA target sites
16. Models of microRNA-target coordination
Part IV. Detection and Quantitation of MicroRNAs: 17. Detection and analysis of microRNAs using LNA (locked nucleic acid)-modified probes
18. Detection and quantitation of microRNAs using the RNA Invader® assay
19. A single molecule method to quantify miRNA gene expression
20. Real-time quantification of MicroRNAs by TaqMan® assays
21. Real-time quantification of miRNAs and mRNAs employing universal reverse transcription
Part V. MicroRNAs in Disease Biology: 22. Dysregulation of microRNAs in human malignancy
23. High throughput microRNAs profiling in cancers
24. Roles of microRNAs in cancer and development
25. MiR-122 in mammalian liver
26. MiRNAs in glioblastoma
27. Role of microRNA pathway in Fragile X mental retardation
28. Insertion of miRNA125b-1 into immunoglobulin heavy chain gene locus mediated by V(D)J recombination in precursor B cell acute lymphoblastic leukemia
29. MiRNAs in TPA-induced differentiation of HL-60 cells
30. MiRNAs in skeletal muscle differentiation
31. Identification and potential function of viral microRNAs
32. Lost in translation: regulation of HIV-1 by microRNAs and a key enzyme of RNA-directed RNA polymerase
Part VI. MicroRNAs in Stem Cell Development: 33. MicroRNAs in the stem cells of the mouse Blastocyst
34. The role of miRNA in hematopoiesis
35. MicroRNAs in embryonic stem cell differentiation and prediction of their targets
36. Generation of single cell microRNA expression profile.
Foreword
Introduction Part I. Discovery of MicroRNAs in Various Organisms: 1. The microRNAs of C. elegans
2. Non-coding RNAs - development of man-made vector-based intronic microRNAs
3. Seeing is believing: strategies for studying microRNA expression
4. MicroRNAs in limb development
5. Identification of miRNAs in plant oryza sativa
Part II. MicroRNA Functions and RNAi-Mediated Pathways: 6. Inhibition of translation initiation by a microRNA
7. In situ analysis of microRNA expression during vertebrate development
8. MicroRNA function in the nervous system
9. Micro RNA expression that controls the amount of branched chain ¿-ketoacid dehydrogenase in mitochondria of human cells
10. MicroRNAs and the regulation of leaf shape
Part III. Computational Biology of MicroRNAs: 11. MiRBase: a database of microRNA sequences, targets and nomenclature
12. Computational prediction of microRNA targets in vertebrates, fruitflies and nematodes
13. Computational approaches to elucidate miRNA biology
14. The RNA hybrid approach to microRNA target prediction
15. Machine learning predicts microRNA target sites
16. Models of microRNA-target coordination
Part IV. Detection and Quantitation of MicroRNAs: 17. Detection and analysis of microRNAs using LNA (locked nucleic acid)-modified probes
18. Detection and quantitation of microRNAs using the RNA Invader® assay
19. A single molecule method to quantify miRNA gene expression
20. Real-time quantification of MicroRNAs by TaqMan® assays
21. Real-time quantification of miRNAs and mRNAs employing universal reverse transcription
Part V. MicroRNAs in Disease Biology: 22. Dysregulation of microRNAs in human malignancy
23. High throughput microRNAs profiling in cancers
24. Roles of microRNAs in cancer and development
25. MiR-122 in mammalian liver
26. MiRNAs in glioblastoma
27. Role of microRNA pathway in Fragile X mental retardation
28. Insertion of miRNA125b-1 into immunoglobulin heavy chain gene locus mediated by V(D)J recombination in precursor B cell acute lymphoblastic leukemia
29. MiRNAs in TPA-induced differentiation of HL-60 cells
30. MiRNAs in skeletal muscle differentiation
31. Identification and potential function of viral microRNAs
32. Lost in translation: regulation of HIV-1 by microRNAs and a key enzyme of RNA-directed RNA polymerase
Part VI. MicroRNAs in Stem Cell Development: 33. MicroRNAs in the stem cells of the mouse Blastocyst
34. The role of miRNA in hematopoiesis
35. MicroRNAs in embryonic stem cell differentiation and prediction of their targets
36. Generation of single cell microRNA expression profile.