Microtubule Organizing Center
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The microtubule-organizing center (MTOC) is a structure found in eukaryotic cells from which microtubules emerge. MTOCs have two main functions: The organization of eukaryotic flagella and cilia and the organization of the mitotic and meiotic spindle apparatus separating the chromosomes during cell division. The MTOC is the site of microtubule nucleation and can be visualized in cells by immunohistochemical detection of -tubulin. In animals, the two most important types of MTOCs are the basal bodies associated with cilia and certain intercellular junctions in epithelial cells, and the centrosome associated with spindle formation.…mehr

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Produktbeschreibung
The microtubule-organizing center (MTOC) is a structure found in eukaryotic cells from which microtubules emerge. MTOCs have two main functions: The organization of eukaryotic flagella and cilia and the organization of the mitotic and meiotic spindle apparatus separating the chromosomes during cell division. The MTOC is the site of microtubule nucleation and can be visualized in cells by immunohistochemical detection of -tubulin. In animals, the two most important types of MTOCs are the basal bodies associated with cilia and certain intercellular junctions in epithelial cells, and the centrosome associated with spindle formation.